A Review of Natural and Modified Betulinic, Ursolic and Echinocystic Acid Derivatives as Potential Antitumor and Anti-HIV Agents

被引：93

作者：

Baglin, I. ^{[1
]}

Mitaine-Offer, A. -C. ^{[1
]}

Nour, M. ^{[1
]}

Tan, K. ^{[1
]}

Cave, C. ^{[1
]}

Lacaille-Dubois, M. -A. ^{[1
]}

机构：

[1] Univ Bourgogne, Fac Pharm, Unite MIB, JE 2244, F-21079 Dijon, France

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2003年 / 3卷 / 06期

关键词：

D O I：

10.2174/1389557033487917

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The aim of this review is to update current knownledge on the betulinic, ursolic and echinocystic acids and their natural and semisynthetic analogs, focussing on their cytotoxic and anti-HIV activities. Then, the last results of the authors' team on unusual semisynthetic derivatives of these triterpenoids will be presented in order to establish structure/activity relationships.

引用

页码：525 / 539

页数：15

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