Inflammation and Its Relationship to Insulin Resistance, Type 2 Diabetes Mellitus, and Endothelial Dysfunction

被引:18
作者
Barzilay, Joshua I. [1 ,2 ]
Freedland, Eric S. [3 ]
机构
[1] Kaiser Permanente Georgia, Dept Med, Atlanta, GA USA
[2] Emory Univ, Sch Med, Div Endocrinol, Atlanta, GA USA
[3] Boston Univ, Sch Med, Dept Emergency Med, Boston Med Ctr, Boston, MA 02118 USA
关键词
D O I
10.1089/154041903321648252
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
In the past decade, clinical, laboratory, and epidemiological research have coalesced to give rise to a new paradigm for understanding type 2 diabetes mellitus (DM). In this review, we present data that DM has an inflammatory etiology and that inflammation plays a role in diabetic complications, especially cardiovascular disease. This new paradigm offers insight into the relationship between DM and obesity. It also suggests posible new avenues of treatment.
引用
收藏
页码:55 / 67
页数:13
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