Fast-track surgery improves postoperative recovery in patients undergoing partial hepatectomy for primary liver cancer: A prospective randomized controlled trial

被引：116

作者：

Ni, C. Y. ^{[1
]}

Yang, Y. ^{[1
,2
]}

Chang, Y. Q. ^{[1
]}

Cai, H. ^{[1
]}

Xu, B. ^{[1
]}

Yang, F. ^{[1
]}

Lau, W. Y. ^{[3
]}

Wang, Z. H. ^{[1
]}

Zhou, W. P. ^{[1
,4
]}

机构：

[1] Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Shanghai 200438, Peoples R China

[2] Second Mil Med Univ, Dept Hlth Stat, Shanghai 200438, Peoples R China

[3] Chinese Univ Hong Kong, Fac Med, Shatin, Hong Kong, Peoples R China

[4] Natl Innovat Alliance Hepatitis & Liver Canc, Shanghai, Peoples R China

来源：

EJSO | 2013年 / 39卷 / 06期

关键词：

Perioperative care; Fast track surgery; Liver neoplasm; Rehabilitation; Hepatectomy; PERIOPERATIVE CARE; SURGICAL COMPLICATIONS; COLORECTAL SURGERY; GASTRIC-CANCER; CLINICAL-TRIAL; PROGRAM; MANAGEMENT; RESECTION; OUTCOMES; CLASSIFICATION;

D O I：

10.1016/j.ejso.2013.03.013

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background and aim: Fast-track surgery (FTS), combining several techniques with evidence-based adjustments, has shown its effectiveness to accelerate recovery, reduce morbidity and shorten hospital stay in many operations. This randomized controlled study was carried out aiming to compare the short-term outcomes of partial hepatectomy for liver cancer managed with FTS or with conventional surgery (CS). Methods: To compare the short-term effects between FTS and CS, a randomized controlled trial was carried out for liver cancer patients undergoing partial hepatectomy from September 2010 to June 2012. Results: Patients with liver cancers before receiving partial hepatectomy were randomized into the FTS group (n = 80) and the CS group (n = 80). Compared with the CS group, the FTS group had significantly less complications (P < 0.05), shorter durations of nausea/vomiting, paralytic ileus and hospital stay, higher general comfort questionnaire measures (GCQ) by Kolcaba Line (all P < 0.05), and lower serum levels of C-reactive Protein on postoperative days 1, 3, and 5. Conclusions: FTS was safe and efficacious. It lessened postoperative stress reactions and accelerated recovery for patients undergoing partial hepatectomy for liver cancer. (c) 2013 Elsevier Ltd. All rights reserved.

引用

页码：542 / 547

页数：6

共 35 条

[1] Educational levels of hospital nurses and surgical patient mortality [J].

Aiken, LH ;

Clarke, SP ;

Cheung, RB ;

Sloane, DM ;

Silber, JH .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 290 (12) :1617-1623

[2]

Akhtar Mohammad Irfan, 2009, J Pak Med Assoc, V59, P154

[3] How does fast track affect quality of care in the emergency department? [J].

Al Darrab, Ayad ;

Fan, Jerome ;

Fernandes, Christopher M. B. ;

Zimmerman, Rosanne ;

Smith, Rhonda ;

Worster, Andrew ;

Smith, Teresa ;

O'Connor, Kelly .

EUROPEAN JOURNAL OF EMERGENCY MEDICINE, 2006, 13 (01) :32-35

[4] Implementation of laparoscopic colectomy with fast-track care in an academic medical center: benefits of a fully ascended learning curve and specialty expertise [J].

Bosio, Raul M. ;

Smith, Bryan M. ;

Aybar, Pablo Serrano ;

Senagore, Anthony J. .

AMERICAN JOURNAL OF SURGERY, 2007, 193 (03) :413-415

[5]

Bosio RM, 2007, AM J SURG, V193, P5

[6] The Clavien-Dindo Classification of Surgical Complications Five-Year Experience [J].

Clavien, Pierre A. ;

Barkun, Jeffrey ;

de Oliveira, Michelle L. ;

Vauthey, Jean Nicolas ;

Dindo, Daniel ;

Schulick, Richard D. ;

de Santibanes, Eduardo ;

Pekolj, Juan ;

Slankamenac, Ksenija ;

Bassi, Claudio ;

Graf, Rolf ;

Vonlanthen, Rene ;

Padbury, Robert ;

Cameron, John L. ;

Makuuchi, Masatoshi .

ANNALS OF SURGERY, 2009, 250 (02) :187-196

[7] 'Fast track' postoperative management protocol for patients with high co-morbidity undergoing complex abdominal and pelvic colorectal surgery [J].

Delaney, CP ;

Fazio, VW ;

Senagore, AJ ;

Robinson, B ;

Halverson, AL ;

Remzi, FH .

BRITISH JOURNAL OF SURGERY, 2001, 88 (11) :1533-1538

[8] Classification of surgical complications - A new proposal with evaluation in a cohort of 6336 patients and results of a survey [J].

Dindo, D ;

Demartines, N ;

Clavien, PA .

ANNALS OF SURGERY, 2004, 240 (02) :205-213

[9] Fast-Track Trials in Palliative Care: An Alternative Randomized Controlled Trial Design [J].

Farquhar, Morag ;

Higginson, Irene J. ;

Booth, Sara .

JOURNAL OF PALLIATIVE MEDICINE, 2009, 12 (03) :213-213

[10] Fast-track management of patients undergoing proximal pancreatic resection [J].

French, J. J. ;

Mansfield, S. D. ;

Jaques, K. ;

Jaques, B. C. ;

Manas, D. M. ;

Charnley, R. M. .

ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, 2009, 91 (03) :201-204

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