Asymmetric induction by the cholestanic moiety on tropos species:: Synthesis and stereochemical characterization of bile acid-based biphenyl phosphites

被引：26

作者：

Iuliano, A. ^{[1
]}

Facchetti, S. ^{[1
]}

Uccello-Barretta, G. ^{[1
]}

机构：

[1] Univ Pisa, Dipartimento Chim & Chim Ind, I-56126 Pisa, Italy

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 13期

关键词：

D O I：

10.1021/jo0606453

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three different bile acid-derived biphenyl phosphites were synthesized, starting from cholic and deoxycholic acids and biphenol, and their stereochemical features were checked by CD and NMR spectroscopies. On the basis of the spectroscopic results, the capability of the cholestanic system to induce a prevalent sense of twist on the biphenyl moiety of the bile acid-derived phosphites as well as their tropos nature was inferred.

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页码：4943 / 4950

页数：8

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