Biphenol-based ligands for Cu-catalyzed asymmetric conjugate addition

被引：47

作者：

Alexakis, A

Polet, D

Benhaim, C

Rosset, S

机构：

[1] Univ Geneva, Dept Organ Chem, CH-1211 Geneva, Switzerland

[2] Univ Texas, Dept Chem & Biochem, Austin, TX 78712 USA

来源：

TETRAHEDRON-ASYMMETRY | 2004年 / 15卷 / 14期

基金：

新加坡国家研究基金会;

关键词：

D O I：

10.1016/j.tetasy.2004.05.016

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The synthesis and characterization of seven new phosphoramidite ligands are described, as well as their use in copper-catalyzed 1,4-addition of diethylzine to a wide range of substrates. Enantioselectivities of up to >99.5% are obtained. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：2199 / 2203

页数：5

共 17 条

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