Enhancing the Toxicity of Cancer Chemotherapeutics with Gold Nanorod Hyperthermia

被引：335

作者：

Hauck, Tanya S. ^{[1
]}

Jennings, Travis L. ^{[1
]}

Yatsenko, Tetyana ^{[2
]}

Kumaradas, J. Carl ^{[2
]}

Chan, Warren C. W. ^{[1
]}

机构：

[1] Univ Toronto, Terrence Donnelly Ctr Cellular & Biomol Res, Inst Biomat & Biomed Engn Mat Sci & Engn Chem Eng, Toronto, ON M5S 3G9, Canada

[2] Ryerson Univ, Dept Phys, Toronto, ON M5B 2K3, Canada

来源：

ADVANCED MATERIALS | 2008年 / 20卷 / 20期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1002/adma.200800921

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The heat produced by optically excited gold nanorods is used to augment the chemotherapeutic agent cisplatin in killing tumor cells. This combined therapy kills 78% more cells than cisplatin alone, suggesting a synergistic interaction between these treatments.

引用

收藏

页码：3832 / +

页数：8

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