Functional, synthetic organic chemical models of cellular ion channels

被引：48

作者：

Gokel, GW

Schlesinger, PH

Djedovic, NK

Ferdani, R

Harder, EC

Hu, JX

Leevy, WM

Pajewska, J

Pajewski, R

Weber, ME

机构：

[1] Washington Univ, Sch Med, Dept Mol Biol & Pharmacol, Div Bioorgan Chem,Program Chem Biol, St Louis, MO 63110 USA

[2] Washington Univ, Sch Med, Dept Cell Biol, St Louis, MO 63110 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 2004年 / 12卷 / 06期

关键词：

synthetic ion channel; cation channel; anion channel; bilayer membrane;

D O I：

10.1016/j.bmc.2003.08.036

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：1291 / 1304

页数：14

共 104 条

[41]

2-V

[42] Synthetic models of cation-conducting channels [J].

Gokel, GW ;

Mukhopadhyay, A .

CHEMICAL SOCIETY REVIEWS, 2001, 30 (05) :274-286

[43]

GOKEL GW, 1991, SYNLETT, P677

[44] A MOLECULAR BLUEPRINT FOR THE PORE-FORMING STRUCTURE OF VOLTAGE-GATED CALCIUM CHANNELS [J].

GROVE, A ;

TOMICH, JM ;

MONTAL, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (15) :6418-6422

[45] A DIRECT COMPARISON OF EXTRACTION AND HOMOGENEOUS BINDING CONSTANTS AS PREDICTORS OF EFFICACY IN ALKALI-METAL CATION-TRANSPORT [J].

HERNANDEZ, JC ;

TRAFTON, JE ;

GOKEL, GW .

TETRAHEDRON LETTERS, 1991, 32 (44) :6269-6272

[46]

HERVE M, 1985, EUR BIOPHYS J BIOPHY, V12, P121, DOI 10.1007/BF00254070

[47]

HILLE B, 2001, IONIC CHANNELS EXC E, V3

[48] Prevention of vascular and neural dysfunction in diabetic rats by C-peptide [J].

Ido, Y ;

Vindigni, A ;

Chang, K ;

Stramm, L ;

Chance, R ;

Heath, WF ;

DiMarchi, RD ;

DiCera, E ;

Williamson, JR .

SCIENCE, 1997, 277 (5325) :563-566

[49]

INOKUMA S, 1988, YUKUGAKU, V37, P441

[50]

Inoue Y., 1990, Cation Binding by Macrocycles

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