Stem cell regulation by JAK/STAT signaling in Drosophila

被引：32

作者：

Gregory, Lorna ^{[1
]}

Came, Paul J. ^{[1
]}

Brown, Stephen ^{[1
]}

机构：

[1] Univ Manchester, Fac Life Sci, Manchester M13 9PT, Lancs, England

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2008年 / 19卷 / 04期

基金：

英国生物技术与生命科学研究理事会; 英国医学研究理事会;

关键词：

Review; JAK/STAT; Stem cell; Blood; Germline;

D O I：

10.1016/j.semcdb.2008.06.003

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Stem cells have become one of the "buzz" topics in the last decade or so. One of the best systems to study adult stem cells in vivo is in the model organism, Drosophila melanogaster. One hundred years of genetic analysis, a sequenced and highly annotated genome and genomics makes this a difficult organism to avoid. The JAK/STAT pathway has been shown to regulate stem cells during haematopoiesis and gametogenesis in Drosophila. In this review we cover the current literature and contrast each group of stem cells with respect to JAK/STAT signaling. (C) 2008 Published by Elsevier Ltd.

引用

页码：407 / 413

页数：7

共 100 条

[71] ALTERATIONS IN THE PRODUCTION OF HEMOCYTES DUE TO A NEOPLASTIC MUTATION OF DROSOPHILA-MELANOGASTER [J].

SILVERS, M ;

HANRATTY, WP .

JOURNAL OF INVERTEBRATE PATHOLOGY, 1984, 44 (03) :324-328

[72] The adult Drosophila malpighian tubules are maintained by multipotent stem cells [J].

Singh, Shree Ram ;

Liu, Wei ;

Hou, Steven X. .

CELL STEM CELL, 2007, 1 (02) :191-203

[73] JAK/STAT signaling regulates tissue outgrowth and male germline stem cell fate in Drosophila [J].

Singh, SR ;

Chen, X ;

Hou, SX .

CELL RESEARCH, 2005, 15 (01) :1-5

[74] DE-cadherin-mediated cell adhesion is essential for maintaining somatic stem cells in the Drosophila ovary [J].

Song, XQ ;

Xie, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (23) :14813-14818

[75] Germline, stem cells anchored by adherens junctions in the Drosophila ovary niches [J].

Song, XQ ;

Zhu, CH ;

Doan, C ;

Xie, T .

SCIENCE, 2002, 296 (5574) :1855-1857

[76] MACROPHAGES AND GLIA PARTICIPATE IN THE REMOVAL OF APOPTOTIC NEURONS FROM THE DROSOPHILA EMBRYONIC NERVOUS-SYSTEM [J].

SONNENFELD, MJ ;

JACOBS, JR .

JOURNAL OF COMPARATIVE NEUROLOGY, 1995, 359 (04) :644-652

[77] Genetic analysis of contributions of dorsal group and JAK-Stat92E pathway genes to larval hemocyte concentration and the egg encapsulation response in drosophila [J].

Sorrentino, RP ;

Melk, JP ;

Govind, S .

GENETICS, 2004, 166 (03) :1343-1356

[78] Cellular immune response to parasite infection in the Drosophila lymph gland is developmentally regulated [J].

Sorrentino, RP ;

Carton, Y ;

Govind, S .

DEVELOPMENTAL BIOLOGY, 2002, 243 (01) :65-80

[79] Moving towards the next generation [J].

Starz-Gaiano, M ;

Lehmann, R .

MECHANISMS OF DEVELOPMENT, 2001, 105 (1-2) :5-18

[80] Live imaging of wound inflammation in Drosophila embryos reveals key roles for small GTPases during in vivo cell migration [J].

Stramer, B ;

Wood, W ;

Galko, MJ ;

Redd, MJ ;

Jacinto, A ;

Parkhurst, SM ;

Martin, P .

JOURNAL OF CELL BIOLOGY, 2005, 168 (04) :567-573

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