Evaluation of a new miniaturized ion mobility spectrometer and its coupling to fast gas chromatography multicapillary columns

被引：18

作者：

Aguilera-Herrador, E. ^{[1
]}

Cardenas, S. ^{[1
]}

Ruzsanyi, V. ^{[2
]}

Sielemann, S. ^{[2
]}

Valcarcel, M. ^{[1
]}

机构：

[1] Univ Cordoba, Dept Analyt Chem, E-14071 Cordoba, Spain

[2] AGnalyt Sensorsyst mbH, D-44229 Dortmund, Germany

来源：

JOURNAL OF CHROMATOGRAPHY A | 2008年 / 1214卷 / 1-2期

关键词：

Ion mobility spectrometry; Miniaturization; Multicapillary columns; Volatile organic compounds;

D O I：

10.1016/j.chroma.2008.10.050

中图分类号：

Q5 [生物化学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

A new miniaturized ion mobility spectrometer (mu IMS) has been constructed and evaluated. The results obtained for a selected group of volatile organic compounds have been compared with those provided by an IMS of bigger dimensions with satisfactory conclusions. Moreover, its performance in terms of analytes resolution is better than those values given for other miniaturized instruments described in the literature. The possibility of an adjustable shutter opening time and the low intensity of the radiation source are also remarkable characteristics of the miniaturized detector. The small size of the mu IMS enables its portability and its wide-range of applications as a sensor device. Six different substances supposed as respiratory markers of different diseases have been selected to prove the feasibility of the spectrometer constructed. (c) 2008 Elsevier B.V. All rights reserved.

引用

页码：143 / 150

页数：8

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