Phenazine natural products: Biosynthesis, synthetic analogues, and biological activity

被引：552

作者：

Laursen, JB

Nielsen, J

机构：

[1] Royal Vet & Agr Univ, Dept Chem, DK-1871 Frederiksberg C, Denmark

[2] Tech Univ Denmark, Dept Chem, Kemitorvet, DK-2800 Kgs Lyngby, Denmark

来源：

CHEMICAL REVIEWS | 2004年 / 104卷 / 03期

关键词：

D O I：

10.1021/cr020473j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review deals exclusively with a representative selection of biologically significant phenazines, their natural occurrence, their biosynthesis, the design and synthesis of analogues, and their biological function and possible mode of action. In particular, phenazines produced by streptomycetes are reviewed. Furthermore, generally recognized methods for phenazine synthesis are covered.

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页码：1663 / 1685

页数：23

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