Palladium/copper (I) halide-cocatalyzed stereospecific coupling of 1-fluorovinylstannanes with aryl iodides and acyl chlorides

被引:43
作者
Chen, C [1 ]
Wilcoxen, K [1 ]
Kim, KI [1 ]
McCarthy, JR [1 ]
机构
[1] NEUROCRINE BIOSCI INC,DEPT MED CHEM,SAN DIEGO,CA 92129
关键词
D O I
10.1016/S0040-4039(97)10003-X
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Cross-coupling of 1-fluorovinylstannanes with aryl iodides or acyl chlorides, cocatalyzed by palladium and copper (I) iodide proceeded under mild conditions to give substituted fluoro olefins and alpha-fluoro-alpha,beta-unsaturated ketones, respectively, in good yields with retention of configuration. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:7677 / 7680
页数:4
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