Pd-Catalyzed β-Selective Direct C-H Bond Arylation of Thiophenes with Aryltrimethylsilanes

被引：89

作者：

Funaki, Kenji ^{[1
]}

Sato, Tetsuo ^{[1
,2
]}

Oi, Shuichi ^{[1
,2
]}

机构：

[1] Tohoku Univ, Grad Sch Engn, Dept Appl Chem, Aoba Ku, Sendai, Miyagi 9808579, Japan

[2] Tohoku Univ, Environm Conservat Res Inst, Aoba Ku, Sendai, Miyagi 9808579, Japan

来源：

ORGANIC LETTERS | 2012年 / 14卷 / 24期

关键词：

CROSS-COUPLING REACTIONS; ARYL HALIDES; DERIVATIVES; SILICON;

D O I：

10.1021/ol3029109

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Direct arylation of thiophenes and benzothiophenes with aryltrimethylsilanes was effectively catalyzed by PdCl2(MeCN)(2) in the presence of CuCl2 as an oxidant. The reaction preferentially occurred at the beta-position of both thiophenes and benzothiophenes.

引用

页码：6186 / 6189

页数：4

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