The human intestinal IgA response; burning questions

被引：22

作者：

Spencer, Jo ^{[1
]}

Klavinskis, Linda S.

Fraser, Louise D.

机构：

[1] Kings Coll London, Sch Med, Peter Gorer Dept Immunobiol, London, England

来源：

FRONTIERS IN IMMUNOLOGY | 2012年 / 3卷

基金：

英国医学研究理事会;

关键词：

human; IgA; gut-associated lymphoid tissue; CLASS SWITCH RECOMBINATION; HUMAN B-CELLS; LYMPHOID-TISSUE; LAMINA PROPRIA; PLASMA-CELLS; DENDRITIC CELLS; T-CELLS; SOMATIC HYPERMUTATION; GASTRIC LYMPHOMA; TIGHT JUNCTION;

D O I：

10.3389/fimmu.2012.00108

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The title of this special topic invites us to identify areas in the field of IgA biology that are uncertain or in need of clarification. The inductive phase of the human intestinal IgA response has been a controversial area for some years. Therefore, to structure this review, we have identified key questions that are debated in this field. We have provided explanations of the origins of the uncertainties and have provided our own reasoned answers to the questions we pose.

引用

页数：10

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