Molecular epidemiology of TTV-like mini virus in Norway

被引：30

作者：

Moen, EM ^{[1
]}

Huang, L ^{[1
]}

Grinde, B ^{[1
]}

机构：

[1] Natl Inst Publ Hlth, Dept Virol, N-0403 Oslo, Norway

来源：

ARCHIVES OF VIROLOGY | 2002年 / 147卷 / 01期

关键词：

D O I：

10.1007/s705-002-8310-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

TT virus (TTV), the first human circovirus to be discovered, appears to be present in most people; less is known about the prevalence of the related TTV-Iike mini virus (TLMV). A sensitive nested PCR, specific for TLMV, detected the virus in 48% of 201 sera (Norwegian blood donors) previously found to have a 90% prevalence of TTV. More samples were either positive for both or negative for both viruses than what would have been expected from a random distribution (p = 0.08). Sequence analysis revealed considerable heterogeneity of Norwegian TLMV as compared to international sequences, suggesting, that TLMV is efficiently dispersed in human populations.

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收藏

页码：181 / 185

页数：5

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