Scaffolds for liver tissue engineering

被引：44

作者：

Hammond, John S.

Beckingham, Ian J.

Shakesheff, Kevin M.

机构：

[1] Univ Nottingham, Sch Pharm, Nottingham NG7 2RD, England

[2] Univ Nottingham Hosp, Dept Surg, Nottingham NG7 2UH, England

来源：

EXPERT REVIEW OF MEDICAL DEVICES | 2006年 / 3卷 / 01期

关键词：

biomaterials; liver regeneration; liver tissue engineering; scaffolds;

D O I：

10.1586/17434440.3.1.21

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

This review focuses on the expanding role for biomaterials and polymer scaffolds in liver tissue engineering. Studies are subdivided into in vitro and in vivo approaches. The in vitro section of the review discusses the challenges specific to liver tissue engineering, and how the choice of scaffold and its structure influences the success of the regenerative medicine strategy. The in vivo section evaluates early attempts to stimulate liver repair with cell and growth factor therapies, their failings and how current approaches aim to solve these problems.

引用

页码：21 / 27

页数：7

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