A tri(potassium sulfonate) derivative of perchlorotriphenylmethyl radical (PTM) as a stable water soluble radical-scavenger of the hydroxyl radical more powerful than 5,5-dimethyl-1-pyrroline-N-oxide

被引：5

作者：

Antonio Mesa, Juan ^{[1
]}

Chavez, Sergei ^{[1
]}

Fajari, Lluis ^{[1
]}

Lluis Torres, Josep ^{[1
]}

Julia, Luis ^{[1
]}

机构：

[1] CSIC, IQAC, Dept Quim Biol & Modelitzacio Mol, ES-08034 Barcelona, Spain

来源：

RSC ADVANCES | 2013年 / 3卷 / 25期

关键词：

ELECTRON-TRANSFER CAPACITY; INDUCED OXIDATIVE STRESS; FENTON REACTION; ANTIOXIDANT ACTIVITY; FLUORESCENT-PROBE; SUPEROXIDE; HYDROGEN; SERIES; ESR; POLYPHENOLS;

D O I：

10.1039/c3ra41499j

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

The tripotassium salt of tris(2,3,5,6-tetrachloro-4-hydroxysulfonylphenyl) methyl radical (3 K+ TSPTM3-) reacts in water with hydroxyl radical very fast with a rate constant (k = 2.4 x 10(11) M-1 s(-1)) much higher than that of the reaction of hydroxyl radical with the spin trap 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) (k = 3.4 x 10(9) M-1 s(-1)). The reaction affects the radical character of the molecule and is monitored by electron paramagnetic resonance (EPR). The hydroxyl radical scavenging is established by the characterization of the resulting water-soluble product as the dipotassium salt of 4-[ bis(2,3,5,6-tetrachloro-4-hydroxysulfonylphenyl) methylene]-2,3,5,6-tetrachlorocyclohexa-2,5-dien-1-one (2).

引用

页码：9949 / 9956

页数：8

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