Pt(II)- or Au(III)-catalyzed [3+2] cycloaddition of metal-containing azomethine ylides: Highly efficient synthesis of the mitosene skeleton

被引：120

作者：

Kusama, H ^{[1
]}

Miyashita, Y ^{[1
]}

Takaya, J ^{[1
]}

Iwasawa, N ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Chem, Meguro Ku, Tokyo 1528551, Japan

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 02期

关键词：

D O I：

10.1021/ol052610f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Only 1-3 mol % of PtCl(2) or AuBr(3) was sufficient to promote generation and [3+2] cycloaddition of transition-metal-containing azomethine ylides derived from M(o-alkynylphenyl)imines bearing an internal alkyne moiety. A highly efficient method for the preparation of synthetically useful tricyclic indole derivatives having a substituent at the 3-position of the indole nucleus was established by this method.

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页码：289 / 292

页数：4

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