An efficient synthesis of morpholin-2-one derivatives using glycolaldehyde dimer by the Ugi multicomponent reaction

被引：72

作者：

Kim, YB

Choi, EH

Keum, G

Kang, SB

Lee, DH

Koh, HY

Kim, YS ^{[1
]}

机构：

[1] Korea Inst Sci & Technol, Biochem Res Ctr, Seoul 130650, South Korea

[2] Sogang Univ, Dept Chem, Seoul 121742, South Korea

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 26期

关键词：

D O I：

10.1021/ol016716w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A new one-pot procedure for the efficient synthesis of novel 3-substituted morpholin-2-one-5-carboxamide derivatives using commercially available glycolaldehyde dimer as a bifunctional component with various alpha -amino acids and isocyanides by the Ugi five-center three-component reaction (U-5C-3CR) was developed.

引用

收藏

页码：4149 / 4152

页数：4

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