Pairwise use of complexity-generating reactions in diversity-oriented organic synthesis

被引：247

作者：

Lee, DS ^{[1
]}

Sello, JK ^{[1
]}

Schreiber, SL ^{[1
]}

机构：

[1] Harvard Univ, Howard Hughes Med Inst, Dept Chem & Chem Biol, Harvard Inst Chem & Cell Biol, Cambridge, MA 02138 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 05期

关键词：

D O I：

10.1021/ol005574n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Two pairs of complexity-generating reactions with an essential product-substrate relationship along a synthetic pathway are demonstrated, This pathway illustrates a key element in a planning algorithm for diversity-oriented synthesis, This element facilitates the efficient synthesis of structurally complex compounds, and it can be integrated with ones that provide structurally diverse compounds.

引用

页码：709 / 712

页数：4

共 38 条

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