Comparative chemical analysis of Radix Astragali and Radix Hedysari by HPLC

被引：32

作者：

Liu, Yi ^{[1
,2
,3
]}

Zhang, Xiaojing ^{[1
,2
]}

Zhao, Yuying ^{[1
,2
]}

Chen, Hubiao ^{[4
]}

Wang, Bin ^{[1
,2
]}

Zhang, Qingying ^{[1
,2
]}

机构：

[1] Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

[2] Peking Univ, Sch Pharmaceut Sci, Dept Nat Med, Hlth Sci Ctr, Beijing 100191, Peoples R China

[3] Natl Inst Food & Drug Control, Beijing 100050, Peoples R China

[4] Hong Kong Baptist Univ, Sch Chinese Med, Hong Kong, Hong Kong, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2012年 / 26卷 / 20期

基金：

中国国家自然科学基金;

关键词：

Radix Astragali; Radix Hedysari; Astragalus membranaceus var. mongholicus; Astragalus membranaceus; Hedysarum polybotrys; HPLC; SAPONINS; IV;

D O I：

10.1080/14786419.2011.619188

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

Radix Astragali and Radix Hedysari, two famous traditional Chinese medicines (TCM), were considered to possess the same efficacy in TCM traditionally. However, modern pharmacological and phytochemical investigations showed that they were different in efficacy and chemical constituents to some degree. In this study, the principal constituents of the two drugs, isoflavonoids and saponins, were comparatively analysed using HPLC-UV and HPLC-ELSD methods. The results showed that there were some common compounds, especially flavonoids, in both drugs, while the differences in the types and contents of their chemical constituents, especially in saponins, were also obvious. The similarities and differences of the chemicals may be responsible, at least partially, for the similarities and differences in their efficacies or bioactivities.

引用

页码：1935 / 1938

页数：4

共 9 条

[1]

Hiroshi H., 1976, PLANTA MED, V30, P297

[2]

KITAGAWA I, 1983, CHEM PHARM BULL, V31, P698

[3]

KUBO M, 1977, Shoyakugaku Zasshi, V31, P82

[4]

Structural determination of saponins from Hedysarum polybotrys [J].