Chemoenzymatic dynamic kinetic resolution

被引：126

作者：

Pàmies, O

Bäckvall, JE

机构：

[1] Univ Rovira & Virgili, Dept Phys & Inorgan Chem, Tarragona 43005, Spain

[2] Stockholm Univ, Arrhenius Lab, Dept Organ Chem, SE-10691 Stockholm, Sweden

来源：

TRENDS IN BIOTECHNOLOGY | 2004年 / 22卷 / 03期

关键词：

D O I：

10.1016/j.tibtech.2004.01.005

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

During the past decade a new concept has appeared in asymmetric catalysis involving the combination of a biocatalyst and a chemocatalyst in one 'pot' leading to efficient deracemization via dynamic kinetic resolution (DKR). Here, we outline the different strategies that have been developed for efficient chemoenzymatic DKR, in particular the powerful combination of an enzyme and a metal catalyst.

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页码：130 / 135

页数：6

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