The lineage commitment of haemopoietic progenitor cells

被引：116

作者：

Cross, MA ^{[1
]}

Enver, T ^{[1
]}

机构：

[1] INST CANC RES,CHESTER BEATTY LABS,LEUKAEMIA RES FUND CTR,LONDON SW3 6JB,ENGLAND

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1997年 / 7卷 / 05期

关键词：

D O I：

10.1016/S0959-437X(97)80007-X

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Multipotent haemopoietic progenitor cells appear to be 'primed' for commitment by co-expression of a multiplicity of genes characteristic of different lineages. Lineage commitment proceeds as the consolidation of a distinct pattern of gene expression out of this milieu.

引用

页码：609 / 613

页数：5

共 53 条

[21] Induction of hematopoietic commitment and erythromyeloid differentiation in embryonal stem cells constitutively expressing c-myb [J].

Melotti, P ;

Calabretta, B .

BLOOD, 1996, 87 (06) :2221-2234

[22] The transcription factors c-myb and GATA-2 act independently in the regulation of normal hematopoiesis [J].

Melotti, P ;

Calabretta, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (11) :5313-5318

[23] Inhibition of granulocytic differentiation by mNotch1 [J].

Milner, LA ;

Bigas, A ;

Kopan, R ;

BrashemStein, C ;

Bernstein, ID ;

Martin, DIK .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (23) :13014-13019

[24]

MILNER LA, 1994, BLOOD, V83, P2057

[25] NF-M (chicken C/EBP beta) induces eosinophilic differentiation and apoptosis in a hematopoietic progenitor cell line [J].

Muller, C ;

KowenzLeutz, E ;

GrieserAde, S ;

Graf, T ;

Leutz, A .

EMBO JOURNAL, 1995, 14 (24) :6127-6135

[26] VINTAGE REDS AND WHITES - COMBINATORIAL TRANSCRIPTION FACTOR UTILIZATION IN HEMATOPOIETIC DIFFERENTIATION [J].

NESS, SA ;

ENGEL, JD .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 1994, 4 (05) :718-724

[27]

NICHOLLS SE, 1995, J IMMUNOL, V155, P845

[28]

Oelgeschlager M, 1996, MOL CELL BIOL, V16, P4717

[29] AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis [J].

Okuda, T ;

vanDeursen, J ;

Hiebert, SW ;

Grosveld, G ;

Downing, JR .

CELL, 1996, 84 (02) :321-330

[30] Development of the hematopoietic system [J].

Orkin, SH .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 1996, 6 (05) :597-602

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