RrgA and RrgB are components of a multisubunit pilus encoded by the Streptococcus pneumoniae rlrA pathogenicity islet

被引：100

作者：

LeMieux, J

Hava, DL

Basset, A

Camilli, A

机构：

[1] Tufts Univ, Sch Med, Howard Hughes Med Inst, Boston, MA 02111 USA

[2] Tufts Univ, Sch Med, Dept Mol Biol & Microbiol, Boston, MA 02111 USA

来源：

INFECTION AND IMMUNITY | 2006年 / 74卷 / 04期

关键词：

D O I：

10.1128/IAI.74.4.2453-2456.2006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The rlrA pathogenicity islet in Streptococcus pneumoniae TIGR4 encodes three surface proteins, RrgA, RrgB, and RrgC, and three sortase enzymes. Using transmission electron microscopy, cell fractionation, cell wall sorting signal domain swapping, and Western blotting, we show that RrgA and RrgB are incorporated into a multisubunit pilus in S. pneumoniae.

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页码：2453 / 2456

页数：4

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