CASA: a server for the critical assessment of protein sequence alignment accuracy

被引:3
作者
Kahsay, RY
Wan, GL
Dongre, N
Gao, G
Dunbrack, RL
机构
[1] Fox Chase Canc Ctr, Inst Canc Res, Philadelphia, PA 19111 USA
[2] Univ Delaware, Delaware Biotechnol Inst, Newark, DE 19711 USA
[3] Univ Delaware, Dept Elect & Comp Engn, Newark, DE 19711 USA
关键词
D O I
10.1093/bioinformatics/18.3.496
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A public server for evaluating the accuracy of protein sequence alignment methods is presented. CASA is an implementation of the alignment accuracy benchmark presented by Sauder et al. (Proteins, 40, 6-22, 2000). The benchmark currently contains 39321 pairwise protein structure alignments produced with the CE program from SCOP domain definitions. The server produces graphical and tabular comparisons of the accuracy of a user's input sequence alignments with other commonly used programs, such as BLAST PSI-BLAST Clustal W, and SAM-T99.
引用
收藏
页码:496 / 497
页数:2
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