Perspectives: Biochemistry - Intramembrane proteases - Mixing oil and water

被引：51

作者：

Wolfe, MS ^{[1
]}

Selkoe, DJ

机构：

[1] Harvard Univ, Sch Med, Ctr Neurol Dis, Boston, MA 02115 USA

[2] Brigham & Womens Hosp, Boston, MA 02115 USA

来源：

SCIENCE | 2002年 / 296卷 / 5576期

关键词：

D O I：

10.1126/science.1073844

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：2156 / 2157

页数：3

共 24 条

[11] Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs [J].

Rawson, RB ;

Zelenski, NG ;

Nijhawan, D ;

Ye, J ;

Sakai, J ;

Hasan, MT ;

Chang, TY ;

Brown, MS ;

Goldstein, JL .

MOLECULAR CELL, 1997, 1 (01) :47-57

[12] Cell surface presenilin-1 participates in the γ-secretase-like proteolysis of notch [J].

Ray, WJ ;

Yao, M ;

Mumm, J ;

Schroeter, EH ;

Saftig, P ;

Wolfe, M ;

Selkoe, DJ ;

Kopan, R ;

Goate, AM .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (51) :36801-36807

[13] Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain [J].

Schroeter, EH ;

Kisslinger, JA ;

Kopan, R .

NATURE, 1998, 393 (6683) :382-386

[14] γ-Secretase, notch, Aβ and Alzheimer's disease:: Where do the presenilins fit in? [J].

Sisodia, SS ;

St George-Hyslop, PH .

NATURE REVIEWS NEUROSCIENCE, 2002, 3 (04) :281-290

[15] γ-secretase:: Never more enigmatic [J].

Sisodia, SS ;

Annaert, W ;

Kim, SH ;

De Strooper, B .

TRENDS IN NEUROSCIENCES, 2001, 24 (11) :S2-S6

[16] Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases [J].

Steiner, H ;

Kostka, M ;

Romig, H ;

Basset, G ;

Pesold, B ;

Hardy, J ;

Capell, A ;

Meyn, L ;

Grim, ML ;

Baumeister, R ;

Fechteler, K ;

Haass, C .

NATURE CELL BIOLOGY, 2000, 2 (11) :848-851

[17] Presenilin is required for activity and nuclear access of Notch in Drosophila [J].

Struhl, G ;

Greenwald, I .

NATURE, 1999, 398 (6727) :522-525

[18] The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor [J].

Tam, A ;

Schmidt, WK ;

Michaelis, S .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (50) :46798-46806

[19] Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors [J].

Thinakaran, G ;

Harris, CL ;

Ratovitski, T ;

Davenport, F ;

Slunt, HH ;

Price, DL ;

Borchelt, DR ;

Sisodia, SS .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (45) :28415-28422

[20] Drosophila Rhomboid-1 defines a family of putative intramembrane serine proteases [J].

Urban, S ;

Lee, JR ;

Freeman, M .

CELL, 2001, 107 (02) :173-182

← 1 2 3 →