Imaging and quantifying transverse flow velocity with the Doppler bandwidth in a phase-resolved functional optical coherence tomography

被引：95

作者：

Ren, HW ^{[1
]}

Brecke, KM

Ding, ZH

Zhao, YH

Nelson, JS

Chen, ZP

机构：

[1] Univ Calif Irvine, Ctr Biomed Engn, Irvine, CA 92612 USA

[2] Univ Calif Irvine, Beckman Laser Inst, Irvine, CA 92612 USA

来源：

OPTICS LETTERS | 2002年 / 27卷 / 06期

关键词：

D O I：

10.1364/OL.27.000409

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

The Doppler bandwidth extracted from the standard deviation of the frequency shift in phase-resolved functional optical coherence tomography (F-OCT) was used to image the velocity component that is transverse to the optical probing beam. It was found that above a certain threshold level the Doppler bandwidth is a linear function of flow velocity and that the effective numerical aperture of the optical objective in the sample arm determines the slope of this dependence. The Doppler bandwidth permits accurate measurement of flow velocity without the need for precise determination of flow direction when the Doppler flow angle is within +/-15degrees perpendicular to the probing beam. Such an approach extends the dynamic range of flow velocity measurements obtained with the phase-resolved F-OCT. (C) 2002 Optical Society of America.

引用

页码：409 / 411

页数：3

共 8 条

[1] Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography [J].

Chen, ZP ;

Milner, TE ;

Srinivas, S ;

Wang, XJ ;

Malekafzali, A ;

vanGemert, MJC ;

Nelson, JS .

OPTICS LETTERS, 1997, 22 (14) :1119-1121

[2] Optical Doppler tomographic imaging of fluid flow velocity in highly scattering media [J].

Chen, ZP ;

Milner, TE ;

Dave, D ;

Nelson, JS .

OPTICS LETTERS, 1997, 22 (01) :64-66

[3] OPTICAL COHERENCE TOMOGRAPHY [J].

HUANG, D ;

SWANSON, EA ;

LIN, CP ;

SCHUMAN, JS ;

STINSON, WG ;

CHANG, W ;

HEE, MR ;

FLOTTE, T ;

GREGORY, K ;

PULIAFITO, CA ;

FUJIMOTO, JG .

SCIENCE, 1991, 254 (5035) :1178-1181

[4] Velocity-estimation accuracy and frame-rate limitations in color Doppler optical coherence tomography [J].

Kulkarni, MD ;

van Leeuwen, TG ;

Yazdanfar, S ;

Izatt, JA .

OPTICS LETTERS, 1998, 23 (13) :1057-1059

[5] In vivo video rate optical coherence tomography [J].

Rollins, AM ;

Kulkarni, MD ;

Yazdanfar, S ;

Ung-arunyawee, R ;

Izatt, JA .

OPTICS EXPRESS, 1998, 3 (06) :219-229

[6] High-speed phase- and group-delay scanning with a grating-based phase control delay line [J].

Tearney, GJ ;

Bouma, BE ;

Fujimoto, JG .

OPTICS LETTERS, 1997, 22 (23) :1811-1813

[7] Doppler standard deviation imaging for clinical monitoring of in vivo human skin blood flow [J].

Zhao, YH ;

Chen, ZP ;

Saxer, C ;

Shen, QM ;

Xiang, SH ;

de Boer, JF ;

Nelson, JS .

OPTICS LETTERS, 2000, 25 (18) :1358-1360

[8] Phase-resolved optical coherence tomography and optical Doppler tomography for imaging blood flow in human skin with fast scanning speed and high velocity sensitivity [J].

Zhao, YH ;

Chen, ZP ;

Saxer, C ;

Xiang, SH ;

de Boer, JF ;

Nelson, JS .

OPTICS LETTERS, 2000, 25 (02) :114-116

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