Surface Functionalization of Gold Nanoparticles with Red Blood Cell Membranes

被引：506

作者：

Gao, Weiwei ^{[1
,2
]}

Hu, Che-Ming J. ^{[1
,2
]}

Fang, Ronnie H. ^{[1
,2
]}

Luk, Brian T. ^{[1
,2
]}

Su, Jing ^{[1
,2
]}

Zhang, Liangfang ^{[1
,2
]}

机构：

[1] Univ Calif San Diego, Dept NanoEngn, La Jolla, CA 92093 USA

[2] Univ Calif San Diego, Moores Canc Ctr, La Jolla, CA 92093 USA

来源：

ADVANCED MATERIALS | 2013年 / 25卷 / 26期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

gold nanoparticles; red blood cells; surface functionalization; biomimetics; nanomedicine; SIALIC-ACID; ERYTHROCYTE; FLUORESCENCE; PROTEIN; SURVIVAL; PLATFORM; CD47;

D O I：

10.1002/adma.201300638

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Gold nanoparticles are enclosed in cellular membranes derived from natural red blood cells (RBCs) by a top-down approach. The gold nanoparticles exhibit a complete membrane surface layer and biological characteristics of the source cells. The combination of inorganic gold nanoparticles with biological membranes is a compelling way to develop biomimetic gold nanostructures for future applications, such as those requiring evasion of the immune system. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：3549 / 3553

页数：5

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