Cyclic ADP-ribose:: A novel Ca2+-mobilising second messenger

被引：72

作者：

Guse, AH ^{[1
]}

机构：

[1] Univ Hamburg, Inst Physiol Chem, Dept Enzyme Chem, D-20146 Hamburg, Germany

来源：

CELLULAR SIGNALLING | 1999年 / 11卷 / 05期

基金：

英国惠康基金;

关键词：

cyclic ADP-ribose; Ca2+ signalling; second messenger; ryanodine receptor; ADP-ribosyl cyclase; higher eukaryotic cells; signal transduction;

D O I：

10.1016/S0898-6568(99)00004-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cyclic ADP-ribose (cADPR) was discovered as a potent Ca2+-mobilising natural compound in sea urchin eggs. Recently, cADPR was reported to stimulate Ca2+ signalling in several higher eukaryotic cell systems (e.g., smooth and cardiac muscle cells, neuronal cells, adrenal chromaffin cells, macrophages, pancreatic acinar cells and T-lymphocytes). The following aspects of the role of cADPR as a Ca2+-mobilising second messenger are reviewed: coupling of metabolism of cADPR to stimulation of receptors in the plasma membrane, properties and pharmacology of Ca2+ release by cADPR and the involvement of cADPR in Ca2+ entry. CELL SIGNAL 11;5:309-316, 1999. (C) 1999 Elsevier Science Inc.

引用

页码：309 / 316

页数：8

共 77 条

[21] Ca2+ signaling in T-lymphocytes [J].

Guse, AH .

CRITICAL REVIEWS IN IMMUNOLOGY, 1998, 18 (05) :419-448

[22] Ca2+ entry induced by cyclic ADP-ribose in intact T-lymphocytes [J].

Guse, AH ;

Berg, I ;

daSilva, CP ;

Potter, BVL ;

Mayr, GW .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (13) :8546-8550

[23] Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose [J].

Guse, AH ;

da Silva, CP ;

Berg, I ;

Skapenko, AL ;

Weber, K ;

Heyer, P ;

Hohenegger, M ;

Ashamu, GA ;

Schulze-Koops, H ;

Potter, BVL ;

Mayr, GW .

NATURE, 1999, 398 (6722) :70-73

[24]

GUSE AH, 1995, J IMMUNOL, V155, P3353

[25] 1-(5-Phospho-beta-D-ribosyl)2'-phosphoadenosine 5'-phosphate cyclic anhydride induced Ca2+ release in human T-cell lines [J].

Guse, AH ;

DaSilva, CP ;

Weber, K ;

Armah, CN ;

Ashamu, GA ;

Schulze, C ;

Potter, BVL ;

Mayr, GW ;

Hilz, H .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 245 (02) :411-417

[26] INVOLVEMENT OF THE BRAIN-TYPE OF RYANODINE RECEPTOR IN T-CELL PROLIFERATION [J].

HAKAMATA, Y ;

NISHIMURA, S ;

NAKAI, J ;

NAKASHIMA, Y ;

KITA, T ;

IMOTO, K .

FEBS LETTERS, 1994, 352 (02) :206-210

[27] PURIFICATION AND CHARACTERIZATION OF A MOLLUSCAN EGG-SPECIFIC NADASE, A 2ND-MESSENGER ENZYME [J].

HELLMICH, MR ;

STRUMWASSER, F .

CELL REGULATION, 1991, 2 (03) :193-202

[28] Muscarinic receptor-mediated dual regulation of ADP-ribosyl cyclase in NG108-15 neuronal cell membranes [J].

Higashida, H ;

Yokoyama, S ;

Hashii, M ;

Taketo, M ;

Higashida, M ;

Takayasu, T ;

Ohshima, T ;

Takasawa, S ;

Okamoto, H ;

Noda, M .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (50) :31272-31277

[29] ADP-ribosyl cyclase coupled with receptors via G proteins [J].

Higashida, H .

FEBS LETTERS, 1997, 418 (03) :355-356

[30] ADP RIBOSYL CYCLASE ACTIVITY OF A NOVEL BONE-MARROW STROMAL CELL-SURFACE MOLECULE, BST-1 [J].

HIRATA, Y ;

KIMURA, N ;

SATO, K ;

OHSUGI, Y ;

TAKASAWA, S ;

OKAMOTO, H ;

ISHIKAWA, J ;

KAISHO, T ;

ISHIHARA, K ;

HIRANO, T .

FEBS LETTERS, 1994, 356 (2-3) :244-248

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