Activation of dendritic cells by polymorphonuclear neutrophils

被引:22
作者
Boudaly, Sarah [1 ]
机构
[1] Univ Paris 07, Inst Univ Hematol, Hop St Louis, CNRS,UMR 7151, Paris, France
来源
FRONTIERS IN BIOSCIENCE-LANDMARK | 2009年 / 14卷
关键词
Neutrophil; Dendritic Cell; Cellular Cooperation; Innate Immunity; Review; REGULATORY T-CELLS; APOPTOTIC CELLS; ADAPTIVE IMMUNITY; LANGERHANS CELLS; CUTTING EDGE; DC-SIGN; RESPONSES; RECEPTOR; INFLAMMATION; MECHANISMS;
D O I
10.2741/3326
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The obsolete view describing neutrophils as innate immune cells that respond rapidly to microbial invasion and then rapidly die by apoptosis is now challenged by several data. In both human and mice, there are now evidences that neutrophils play a role in dendritic cell activation, a critical step for the outcome of the specific T cell response.
引用
收藏
页码:1589 / 1595
页数:7
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