CART peptides: novel addiction- and feeding-related neuropeptides

被引：152

作者：

Kuhar, MJ ^{[1
]}

Dall Vechia, SE ^{[1
]}

机构：

[1] Emory Univ, Yerkes Reg Primate Res Ctr, Atlanta, GA 30329 USA

来源：

TRENDS IN NEUROSCIENCES | 1999年 / 22卷 / 07期

关键词：

D O I：

10.1016/S0166-2236(98)01377-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

CART peptides are novel,putative brain-gut neurotransmitters and co-transmitters that probably have a role in drug abuse, the control of feeding behavior, sensory processing, stress and development. They are abundant, processed and apparently released. Exogenously applied peptides cause inhibition of feeding and have neurotrophic properties. Although the precise sequences, relative abundance and efficacy of all CART peptides are currently being determined, small molecules that are active at putative CART receptors could have substantial therapeutic promise.

引用

页码：316 / 320

页数：5

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