Hybrid Semiconducting Polymer Dot-Quantum Dot with Narrow-Band Emission, Near-Infrared Fluorescence, and High Brightness

被引：111

作者：

Chan, Yang-Hsiang ^{[1
]}

Ye, Fangmao ^{[1
]}

Gallina, Maria Elena ^{[1
]}

Zhang, Xuanjun ^{[1
]}

Jin, Yuhui ^{[1
]}

Wu, I-Che ^{[1
]}

Chiu, Daniel T. ^{[1
]}

机构：

[1] Univ Washington, Dept Chem, Seattle, WA 98195 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2012年 / 134卷 / 17期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

NANOPARTICLES; NANOSTRUCTURES; ULTRABRIGHT;

D O I：

10.1021/ja3022973

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

This communication describes a new class of semiconducting polymer nanoparticle-quantum dot hybrid with high brightness, narrow emission, near-IR fluorescence, and excellent cellular targeting capability. Using this approach, we circumvented the current difficulty with obtaining narrow-band-emitting and near-IR-fluorescing semiconducting polymer nanoparticles while combining the advantages of both semiconducting polymer nanoparticles and quantum dots. We further demonstrated the use of this new class of hybrid nanomaterial for effective and specific cellular and subcellular labeling without any noticeable nonspecific binding. This hybrid nonmaterial is anticipated to find use in a variety of in vitro and in vivo biological applications.

引用

页码：7309 / 7312

页数：4

共 28 条

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Preparation of functional magnetic nanocomposites and hybrid materials: recent progress and future directions [J].