Dynamic combinatorial chemistry: The unexpected choice of receptors by guest molecules

被引：66

作者：

de Bruin, B ^{[1
]}

Hauwert, P ^{[1
]}

Reek, JNH ^{[1
]}

机构：

[1] Univ Amsterdam, Vant Hoff Inst Mol Sci, NL-1018 WS Amsterdam, Netherlands

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 17期

关键词：

dynamic combinatorial chemistry; molecular recognition; receptors; supramolecular chemistry;

D O I：

10.1002/anie.200504480

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Survival of the fittest? Amplification of the best receptor from a dynamic combinatorial library does not always proceed according to survival of the "fittest". However, it has recently resulted in the discovery of some unexpected receptors for various substrates, as illustrated by the example of a catenane receptor (see picture; green) for the neurotransmitter acetylcholine (red). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2660 / 2663

页数：4

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