Lymphangiogenesis in development and human disease

被引:969
作者
Alitalo, K
Tammela, T
Petrova, TV
机构
[1] Univ Helsinki, Ludwig Inst Canc Res, Mol Canc Biol Lab, FIN-00014 Helsinki, Finland
[2] Univ Helsinki, Biomedicum Helsinki, Mol Cell Biol Program, Haartman Inst, FIN-00014 Helsinki, Finland
[3] Univ Helsinki, Cent Hosp, FIN-00014 Helsinki, Finland
基金
芬兰科学院; 美国国家卫生研究院;
关键词
D O I
10.1038/nature04480
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The lymphatic vasculature forms a vessel network that drains interstitial fluid from tissues and returns it to the blood. Lymphatic vessels are also an essential part of the body's immune defence. They have an important role in the pathogenesis of several diseases, such as cancer, lymphoedema and various inflammatory conditions. Recent biological and technological developments in lymphatic vascular biology will lead to a better understanding and treatment of these diseases.
引用
收藏
页码:946 / 953
页数:8
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