Lymphangiogenesis in development and human disease

被引：969

作者：

Alitalo, K

Tammela, T

Petrova, TV

机构：

[1] Univ Helsinki, Ludwig Inst Canc Res, Mol Canc Biol Lab, FIN-00014 Helsinki, Finland

[2] Univ Helsinki, Biomedicum Helsinki, Mol Cell Biol Program, Haartman Inst, FIN-00014 Helsinki, Finland

[3] Univ Helsinki, Cent Hosp, FIN-00014 Helsinki, Finland

来源：

NATURE | 2005年 / 438卷 / 7070期

基金：

芬兰科学院; 美国国家卫生研究院;

关键词：

D O I：

10.1038/nature04480

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The lymphatic vasculature forms a vessel network that drains interstitial fluid from tissues and returns it to the blood. Lymphatic vessels are also an essential part of the body's immune defence. They have an important role in the pathogenesis of several diseases, such as cancer, lymphoedema and various inflammatory conditions. Recent biological and technological developments in lymphatic vascular biology will lead to a better understanding and treatment of these diseases.

引用

页码：946 / 953

页数：8

共 100 条

[61] Cancer cells compress intratumour vessels
Padera, TP
Stoll, BR
Tooredman, JB
Capen, D
di Tomaso, E
Jain, RK
[J]. NATURE, 2004, 427 (6976) : 695 - 695
[62] Lymphatic metastasis in the absence of functional intratumor lymphatics
Padera, TP
Kadambi, A
di Tomaso, E
Carreira, CM
Brown, EB
Boucher, Y
Choi, NC
Mathisen, D
Wain, J
Mark, EJ
Munn, LL
Jain, RK
[J]. SCIENCE, 2002, 296 (5574) : 1883 - 1886
[63] Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
Pennisi, D
Gardner, J
Chambers, D
Hosking, B
Peters, J
Muscat, G
Abbott, C
Koopman, P
[J]. NATURE GENETICS, 2000, 24 (04) : 434 - 437
[64] Pepper MS, 2001, CLIN CANCER RES, V7, P462
[65] Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis
Petrova, TV
Karpanen, T
Norrmén, C
Mellor, R
Tamakoshi, T
Finegold, D
Ferrell, R
Kerjaschki, D
Mortimer, P
Yla-Herttuala, S
Miura, N
Alitalo, K
[J]. NATURE MEDICINE, 2004, 10 (09) : 974 - 981
[66] Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor
Petrova, TV
Mäkinen, T
Mäkelä, TP
Saarela, J
Virtanen, I
Ferrell, RE
Finegold, DN
Kerjaschki, D
Ylä-Herttuala, S
Alitalo, K
[J]. EMBO JOURNAL, 2002, 21 (17) : 4593 - 4599
[67] Molecular characterization of lymphatic endothelial cells
Podgrabinska, S
Braun, P
Velasco, P
Kloos, B
Pepper, MS
Jackson, DG
Skobe, M
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (25) : 16069 - 16074
[68] Proliferation of lymphatics in inflammation
Pullinger, BD
Florey, HW
[J]. JOURNAL OF PATHOLOGY AND BACTERIOLOGY, 1937, 45 (01): : 157 - 170
[69] Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells
Rajantie, I
Ilmonen, M
Alminaite, A
Ozerdem, U
Alitalo, K
Salven, P
[J]. BLOOD, 2004, 104 (07) : 2084 - 2086
[70] VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses
Rissanen, TT
Markkanen, JE
Gruchala, M
Heikura, T
Puranen, A
Kettunen, MI
Kholová, I
Kauppinen, RA
Achen, MG
Stacker, SA
Alitalo, K
Ylä-Herttuala, S
[J]. CIRCULATION RESEARCH, 2003, 92 (10) : 1098 - 1106

← 1 2 3 4 5 6 7 8 9 10 →