Nucleic acid enzymes

被引:64
作者
Fiammengo, R [1 ]
Jäschke, A [1 ]
机构
[1] Heidelberg Univ, Inst Pharm & Mol Biotechnol, D-69120 Heidelberg, Germany
关键词
D O I
10.1016/j.copbio.2005.10.006
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Since the discovery of the first natural ribozyme more than 20 years ago, it has become clear that nucleic acids are not only the static depository of genetic information, but also possess intriguing catalytic activity. The number of reactions catalyzed by engineered nucleic acid enzymes is growing continuously. The versatility of these catalysts supports the idea of an ancestral world based on RNA predating the emergence of proteins, and also drives many studies towards practical applications for nucleic acid enzymes.
引用
收藏
页码:614 / 621
页数:8
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