Radiation dose from a phosphorous-32 impregnated wire mesh vascular stent

被引:59
作者
Janicki, C
Duggan, DM
Coffey, CW
Fischell, DR
Fischell, TA
机构
[1] VANDERBILT UNIV, CTR MED, NASHVILLE, TN 37232 USA
[2] ISOSTENT INC, FAIR HAVEN, NJ 07704 USA
[3] HEART INST BORGESS, KALAMAZOO, MI 49001 USA
关键词
dosimetry; P-32; stent; restenosis;
D O I
10.1118/1.597910
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The near field dose distribution of a realistic vascular stent impregnated with radioactive P-32 is calculated employing the dose-point-kernel (DPK) method in a homogeneous and uniform medium. The cylindrical wire mesh geometry for the Palmaz-Schatz(TM) [Palmaz-Schatz is a tradename of Cordis (a Johnson & Johnson company)] stent is incorporated in the model calculation, and the dose distribution generated by the beta particles emitted from the decayed radioactive P-32 is computed at distances ranging from 0.1 to 2 mm exterior to the stent surface. Dose measurements were obtained using radiochromic film dosimetry media on an actual Palmaz-Schatz half-stent impregnated with P-32 using ion implantation, and compared to the DPK model predictions. The close agreement between the model calculation and the film dosimetry data confirms the validity of the model which can be adapted to a variety of different stent designs. (C) 1997 American Association of Physicists in Medicine.
引用
收藏
页码:437 / 445
页数:9
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