The utility of whole-body diffusion-weighted MRI for delineating regions of interest in PET

被引：3

作者：

Blackledge, M. D. ^{[1
,2
,3
]}

Koh, D. M. ^{[4
]}

Collins, D. J. ^{[1
,2
,3
]}

Chua, S. ^{[5
]}

Leach, M. O. ^{[1
,2
,3
]}

机构：

[1] CR UK, Surrey, England

[2] Inst Canc Res, EPSRC Canc Imaging Ctr, Surrey, England

[3] Royal Marsden Hosp, Surrey, England

[4] Royal Marsden Hosp NHS Fdn Trust, Dept Radiol, Surrey, England

[5] Royal Marsden Hosp NHS Fdn Trust, Dept Nucl Med & PET, Surrey, England

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2013年 / 702卷

基金：

英国工程与自然科学研究理事会; 美国国家卫生研究院;

关键词：

Diffusion-weighted MRI; PET/CT; PET/MRI; Cancer biomarkers; Lymphoma; SUV; UPTAKE VALUES; ONCOLOGY;

D O I：

10.1016/j.nima.2012.08.083

中图分类号：

TH7 [仪器、仪表];

学科分类号：

080401 [精密仪器及机械];

摘要：

In this technological report, we investigate the utility of whole-body diffusion-weighted MRI (WBDWI) as a prior for defining regions of interest (ROI) in PET data. Due to its comparatively high resolution and excellent lesion-to-background ratio, semi-automatic segmentation is possible in WBDWI. Following rigid registration of PET to WBDWI, a simple, fast and automatic algorithm can be used to define ROIs in PET data. This approach is applied to a test cohort of patients diagnosed with lymphoma who underwent both (18)FDG-PET/CT and WBDWI studies to demonstrate its potential application. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：148 / 151

页数：4

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