An efficient and rapid chalcogenide-Morita-Baylis-Hillman process promoted by TBDMSOTf and a thiolane

被引：19

作者：

Rao, Jamjanam Srivardhana

Briere, Jean-Francois

Metzner, Patrick

Basavaiah, Deevi

机构：

[1] Univ Caen, ENSI, CNRS, UMR 6507,Lab Chim Mol & Thioorga, F-14050 Caen, France

[2] Univ Hyderabad, Sch Chem, Hyderabad 500046, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 21期

关键词：

chalcogenide-Morita-Baylis-Hillman; TBDMSOTf; sulfide; enone; acetal;

D O I：

10.1016/j.tetlet.2006.03.070

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ability of the combination of sulfide/TBDMSOTf to promote a chalcogenide-Morita-Baylis-Hillman reaction is reported. The original Michael-Mukaiyama-retroaldol sequence took place and furnished the MBH adducts from the corresponding enones and acetals. This one step process could be performed smoothly at low temperatures (-20 to -50 degrees C) and is rapidly completed within a few hours. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：3553 / 3556

页数：4

共 45 条

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