Desulfurization and transformation of isothiocyanates to cyanamides by using sodium bis(trimethylsilyl)amide

被引:37
作者
Chen, Chun-Yen [2 ]
Wong, Fung Fuh [1 ]
Huang, Jiann-Jyh [3 ]
Lin, Shao-Kai [4 ]
Yeh, Mou-Yung [2 ]
机构
[1] China Med Univ, Grad Inst Pharmaceut Chem, Taichung 40402, Taiwan
[2] Natl Cheng Kung Univ, Dept Chem, Tainan 70101, Taiwan
[3] Dev Ctr Biotechnol, Xizhi City, Taipei County, Taiwan
[4] Natl Cheng Kung Univ, Sustainable Environm Res Ctr, Tainan 709, Taiwan
关键词
Cyanamides; Isothiocyanates; Sodium bis(trimethylsilyl)amide; Desulfurization;
D O I
10.1016/j.tetlet.2008.08.106
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Sodium bis(trimethylsilyl)amide was first used as the desulfurizing agent for the conversion of isothiocyanates to cyanamides in a 'one-flask' reaction. Crown Copyright (C) 2008 Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:6505 / 6507
页数:3
相关论文
共 37 条
[21]  
2-D
[22]   2-Cyanopyridazin-3(2H)-ones:: effective and chemoselective electrophilic cyanating agents [J].
Kim, JJ ;
Kweon, DH ;
Cho, SD ;
Kim, HK ;
Jung, EY ;
Lee, SG ;
Falck, JR ;
Yoon, YJ .
TETRAHEDRON, 2005, 61 (24) :5889-5894
[23]   UBER DIE EINWIRKUNG VON NATRIUM-BIS-TRIMETHYLSILYL-AMID AUF BENZOPHENON, BENZALDEHYD UND BENZOCHINON [J].
KRUGER, C ;
WANNAGAT, U ;
ROCHOW, EG .
CHEMISCHE BERICHTE-RECUEIL, 1963, 96 (08) :2132-&
[24]  
Paquette L.A., 1995, ENCY REAGENTS ORGANI
[25]   A simple and efficient asymmetric synthesis of 3-alkyl-isoindolin-1-ones [J].
Pérard-Viret, J ;
Prangé, T ;
Tomas, A ;
Royer, J .
TETRAHEDRON, 2002, 58 (25) :5103-5108
[26]   SYNTHESIS AND STRUCTURE-ACTIVITY STUDIES OF N,N'-DIARYLGUANIDINE DERIVATIVES - N-(1-NAPHTHYL)-N'-(3-ETHYLPHENYL)-N'-METHYLGUANIDINE - A NEW, SELECTIVE NONCOMPETITIVE NMDA RECEPTOR ANTAGONIST [J].
REDDY, NL ;
HU, LY ;
COTTER, RE ;
FISCHER, JB ;
WONG, WJ ;
MCBURNEY, RN ;
WEBER, E ;
HOLMES, DL ;
WONG, ST ;
PRASAD, R ;
KEANA, JFW .
JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (02) :260-267
[27]   N-aryl N′-hydroxyguanidines, a new class of NO-donors after selective oxidation by nitric oxide synthases:: Structure-activity relationship [J].
Renodon-Cornière, A ;
Dijols, S ;
Perollier, C ;
Lefevre-Groboillot, D ;
Boucher, JL ;
Attias, R ;
Sari, MA ;
Stuehr, D ;
Mansuy, D .
JOURNAL OF MEDICINAL CHEMISTRY, 2002, 45 (04) :944-954
[28]   DIPHENYLCYANAMIDE DERIVATIVES [J].
ROBINSON, JR ;
BROWN, WH .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1951, 29 (12) :1069-1074
[29]  
RUPPERT I, 1977, TETRAHEDRON LETT, V18, P1987
[30]  
SANEYOSH.M, 1968, CHEM PHARM BULL, V16, P505