DNA polymerization on gold nanoparticles through rolling circle amplification: Towards novel scaffolds for three-dimensional periodic nanoassemblies

被引:110
作者
Zhao, WA
Gao, Y
Kandadai, SA
Brook, MA
Li, YF
机构
[1] McMaster Univ, Dept Chem, Hamilton, ON L8N 3Z5, Canada
[2] McMaster Univ, Dept Biochem & Biomed Sci, Hamilton, ON L8N 3Z5, Canada
关键词
DNA; DNA amplification; gold nanotechnology; self-assembly;
D O I
10.1002/anie.200600061
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Ever-increasing through circles: Long single-stranded DNA molecules with repetitive sequence units were synthesized on gold nanoparticles through rolling circle amplification (RCA, see scheme). These special DNA-AuNP conjugates were then used as a scaffold for assembling periodic 3D nanostructures, which may find applications in nanocomputing devices, nanoelectronic circuits, and ultrasensitive biosensors. (Figure Presented) © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:2409 / 2413
页数:5
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