The roles of excessive gastro-oesophageal reflux, disordered oesophageal motility and decreased mucosal sensitivity in the pathogenesis of Barrett's oesophagus

被引：25

作者：

Niemantsverdriet, EC

Timmer, R

Breumelhof, R

Smout, AJPM

机构：

来源：

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 1997年 / 9卷 / 05期

关键词：

Barrett's oesophagus; GORD; oesophageal acid exposure; oesophageal motility; oesophageal mucosal sensitivity;

D O I：

10.1097/00042737-199705000-00019

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Barrett's oesophagus is often considered an end stage of gastro-oesophageal reflux disease. In its pathogenesis increased oesophageal acid exposure, disturbed oesophageal motility and decreased oesophageal mucosal sensitivity are thought to be of importance. In this review the role of each of these factors will be discussed and an update of the recent literature will be given.

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页码：515 / 519

页数：5

相关论文

共 42 条

[1] ROLE OF INTRAGASTRIC AND INTRAESOPHAGEAL ALKALINIZATION IN THE GENESIS OF COMPLICATIONS IN BARRETT COLUMNAR LINED LOWER ESOPHAGUS [J].

ATTWOOD, SEA ;

BALL, CS ;

BARLOW, AP ;

JENKINSON, L ;

NORRIS, TL ;

WATSON, A .

GUT, 1993, 34 (01) :11-15

[2] CONCENTRATION OF REFLUXED ACID AND ESOPHAGEAL MUCOSAL INJURY [J].

BREMNER, RM ;

CROOKES, PF ;

DEMEESTER, TR ;

PETERS, JH ;

STEIN, HJ .

AMERICAN JOURNAL OF SURGERY, 1992, 164 (05) :522-527

[3] AMBULATORY ESOPHAGEAL BILE REFLUX MONITORING IN BARRETTS-ESOPHAGUS [J].

CALDWELL, MTP ;

LAWLOR, P ;

BYRNE, PJ ;

WALSH, TN ;

HENNESSY, TPJ .

BRITISH JOURNAL OF SURGERY, 1995, 82 (05) :657-660

[4] BARRETTS-ESOPHAGUS - AGE, PREVALENCE, AND EXTENT OF COLUMNAR EPITHELIUM [J].

CAMERON, AJ ;

LOMBOY, CT .

GASTROENTEROLOGY, 1992, 103 (04) :1241-1245

[5] PREVALENCE OF COLUMNAR-LINED (BARRETT) ESOPHAGUS - COMPARISON OF POPULATION-BASED CLINICAL AND AUTOPSY FINDINGS [J].

CAMERON, AJ ;

ZINSMEISTER, AR ;

BALLARD, DJ ;

CARNEY, JA .

GASTROENTEROLOGY, 1990, 99 (04) :918-922

[6] DUODENOGASTROESOPHAGEAL REFLUX - RELATIONSHIP TO PH AND IMPORTANCE IN BARRETTS-ESOPHAGUS [J].

CHAMPION, G ;

RICHTER, JE ;

VAEZI, MF ;

SINGH, S ;

ALEXANDER, R .

GASTROENTEROLOGY, 1994, 107 (03) :747-754

[7]

FAHMY N, 1993, AM J GASTROENTEROL, V88, P1262

[8] BARRETTS-ESOPHAGUS AND OTHER MUCOSAL EVIDENCE OF REFLUX IN ASYMPTOMATIC SUBJECTS WITH ABNORMAL 24-HOUR ESOPHAGEAL PH MONITORING [J].

FASS, R ;

SAMPLINER, RE .

DIGESTIVE DISEASES AND SCIENCES, 1994, 39 (02) :423-425

[9]

FIORUCCI S, 1989, AM J GASTROENTEROL, V84, P1263

[10] BARRETTS-ESOPHAGUS - PH PROFILE [J].

GILLEN, P ;

KEELING, P ;

BYRNE, PJ ;

HENNESSY, TPJ .

BRITISH JOURNAL OF SURGERY, 1987, 74 (09) :774-776

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