The roles of excessive gastro-oesophageal reflux, disordered oesophageal motility and decreased mucosal sensitivity in the pathogenesis of Barrett's oesophagus

被引:25
作者
Niemantsverdriet, EC
Timmer, R
Breumelhof, R
Smout, AJPM
机构
关键词
Barrett's oesophagus; GORD; oesophageal acid exposure; oesophageal motility; oesophageal mucosal sensitivity;
D O I
10.1097/00042737-199705000-00019
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Barrett's oesophagus is often considered an end stage of gastro-oesophageal reflux disease. In its pathogenesis increased oesophageal acid exposure, disturbed oesophageal motility and decreased oesophageal mucosal sensitivity are thought to be of importance. In this review the role of each of these factors will be discussed and an update of the recent literature will be given.
引用
收藏
页码:515 / 519
页数:5
相关论文
共 42 条
[31]   PATTERNS OF ACID REFLUX IN COMPLICATED ESOPHAGITIS [J].
ROBERTSON, D ;
ALDERSLEY, M ;
SHEPHERD, H ;
SMITH, CL .
GUT, 1987, 28 (11) :1484-1488
[32]   BARRETTS ESOPHAGUS - ITS PREVALENCE AND ASSOCIATION WITH ADENOCARCINOMA IN PATIENTS WITH SYMPTOMS OF GASTROESOPHAGEAL REFLUX [J].
SARR, MG ;
HAMILTON, SR ;
MARRONE, GC ;
CAMERON, JL .
AMERICAN JOURNAL OF SURGERY, 1985, 149 (01) :187-193
[33]   Time pattern of gastric acidity in Barrett's esophagus [J].
Savarino, V ;
Mela, GS ;
Zentilin, P ;
Mele, MR ;
Mansi, C ;
Remagnino, AC ;
Vigneri, S ;
Malesci, A ;
Belicchi, M ;
Lapertosa, G ;
Celle, G .
DIGESTIVE DISEASES AND SCIENCES, 1996, 41 (07) :1379-1383
[34]  
SINGH P, 1994, AM J GASTROENTEROL, V89, P349
[35]   DETERMINANTS OF ESOPHAGEAL ALKALINE PH ENVIRONMENT IN CONTROLS AND PATIENTS WITH GASTROESOPHAGEAL REFLUX DISEASE [J].
SINGH, S ;
BRADLEY, LA ;
RICHTER, JE .
GUT, 1993, 34 (03) :309-316
[36]   FUNCTIONAL FOREGUT ABNORMALITIES IN BARRETTS-ESOPHAGUS [J].
STEIN, HJ ;
HOEFT, S ;
DEMEESTER, TR .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1993, 105 (01) :107-111
[37]  
STEIN HJ, 1990, SURGERY, V108, P769
[38]   SYNERGISM OF ACID AND DUODENOGASTROESOPHAGEAL REFLUX IN COMPLICATED BARRETTS-ESOPHAGUS [J].
VAEZI, MF ;
RICHTER, JE .
SURGERY, 1995, 117 (06) :699-704
[39]   Role of acid and duodenogastroesophageal reflux in gastroesophageal reflux disease [J].
Vaezi, MF ;
Richter, JE .
GASTROENTEROLOGY, 1996, 111 (05) :1192-1199
[40]   Barrett's Esophagus A Prevalent, Occult Complication of Gastroesophageal Reflux Disease [J].
Winters, Charles, Jr. ;
Spurling, Timothy J. ;
Chobanian, Sarkis J. ;
Curtis, David J. ;
Esposito, Regina L. ;
Hacker, Joseph F., III ;
Johnson, David A. ;
Cruess, David F. ;
Cotelingam, J. D. ;
Gurney, Michael S. ;
Cattau, Edward L., Jr. .
GASTROENTEROLOGY, 1987, 92 (01) :118-124