The roles of excessive gastro-oesophageal reflux, disordered oesophageal motility and decreased mucosal sensitivity in the pathogenesis of Barrett's oesophagus

被引：25

作者：

Niemantsverdriet, EC

Timmer, R

Breumelhof, R

Smout, AJPM

机构：

来源：

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 1997年 / 9卷 / 05期

关键词：

Barrett's oesophagus; GORD; oesophageal acid exposure; oesophageal motility; oesophageal mucosal sensitivity;

D O I：

10.1097/00042737-199705000-00019

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Barrett's oesophagus is often considered an end stage of gastro-oesophageal reflux disease. In its pathogenesis increased oesophageal acid exposure, disturbed oesophageal motility and decreased oesophageal mucosal sensitivity are thought to be of importance. In this review the role of each of these factors will be discussed and an update of the recent literature will be given.

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页码：515 / 519

页数：5

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