What makes platelets angry - Diabetes, fibrinogen, obesity, and impaired response to antiplatelet therapy?

被引:32
作者
Bhatt, Deepak L. [1 ,2 ]
机构
[1] VA Boston Healthcare Syst, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Boston, MA 02115 USA
关键词
diabetes; platelets;
D O I
10.1016/j.jacc.2008.06.027
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1060 / 1061
页数:2
相关论文
共 20 条
[1]   Excess dosing of antiplatelet and antithrombin agents in the treatment of non-ST-segment elevation acute coronary syndromes [J].
Alexander, KP ;
Chen, AY ;
Roe, MT ;
Newby, LK ;
Gibson, CM ;
Allen-LaPointe, NM ;
Pollack, C ;
Gibler, WB ;
Ohman, EM ;
Peterson, ED .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2005, 294 (24) :3108-3116
[2]   Elevated plasma fibrinogen and diabetes mellitus are associated with lower inhibition of platelet reactivity with clopidogrel [J].
Ang, Lawrence ;
Palakodeti, Vachaspathi ;
Khalid, Ahmer ;
Tsimikas, Sotirios ;
Idrees, Zaheib ;
Tran, Phillip ;
Clopton, Paul ;
Zafar, Nayab ;
Bromberg-Marin, Guilherme ;
Keramati, Shahin ;
Mahmud, Ehtisham .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 52 (13) :1052-1059
[3]   Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease [J].
Angiolillo, Dominick J. ;
Bernardo, Esther ;
Sabate, Manel ;
Jimenez-Quevedo, Pilar ;
Costa, Marco A. ;
Palazuelos, Jorge ;
Hernandez-Antolin, Rosana ;
Moreno, Raul ;
Escaned, Javier ;
Alfonso, Fernando ;
Banuelos, Camino ;
Guzman, Luis A. ;
Bass, Theodore A. ;
Macaya, Carlos ;
Fernandez-Ortiz, Antonio .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2007, 50 (16) :1541-1547
[4]   Randomized comparison of a high clopidogrel maintenance dose in patients with diabetes mellitus and coronary artery disease - Results of the Optimizing antiPlatelet Therapy In diabetes MellitUS (OPTIMUS) study [J].
Angiolillo, Dominick J. ;
Shoemaker, Steven B. ;
Desai, Bhaloo ;
Yuan, Hang ;
Charlton, Ronald K. ;
Bernardo, Esther ;
Zenni, Martin M. ;
Guzman, Luis A. ;
Bass, Theodore A. ;
Costa, Marco A. .
CIRCULATION, 2007, 115 (06) :708-716
[5]  
Angiolillo Dominick J, 2004, J Invasive Cardiol, V16, P169
[6]   Intensifying platelet inhibition - Navigating between scylla and charybdis [J].
Bhatt, Deepak L. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (20) :2078-2081
[7]   Abciximab reduces mortality in diabetics following percutaneous coronary intervention [J].
Bhatt, DL ;
Marso, SP ;
Lincoff, AM ;
Wolski, KE ;
Ellis, SG ;
Topol, EJ .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 35 (04) :922-928
[8]   Aspirin resistance: More than just a laboratory curiosity [J].
Bhatt, DL .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2004, 43 (06) :1127-1129
[9]   Amplified benefit of Clopidogrel versus aspirin in patients with diabetes mellitus [J].
Bhatt, DL ;
Marso, SP ;
Hirsch, AT ;
Ringleb, PA ;
Hacke, W ;
Topol, EJ .
AMERICAN JOURNAL OF CARDIOLOGY, 2002, 90 (06) :625-+
[10]   Assessing the current role of platelet function testing [J].
Braunwald, Eugene ;
Angiolillo, Dominick ;
Bates, Eric ;
Berger, Peter B. ;
Hatt, Deepak ;
Cannon, Christopher P. ;
Furman, Mark I. ;
Gurbel, Paul ;
Michelson, Alan D. ;
Peterson, Eric ;
Wiviott, Stephen .
CLINICAL CARDIOLOGY, 2008, 31 (03) :I10-I16