In Vitro Activity of OPT-80 Tested against Clinical Isolates of Toxin-Producing Clostridium difficile

被引：51

作者：

Karlowsky, James A. ^{[1
]}

Laing, Nancy M. ^{[1
]}

Zhanel, George G. ^{[1
]}

机构：

[1] Univ Manitoba, Fac Med, Dept Med Microbiol & Infect Dis, Winnipeg, MB, Canada

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2008年 / 52卷 / 11期

关键词：

D O I：

10.1128/AAC.00476-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Agar dilution antimicrobial susceptibility testing (CLSI, M11-A7, 2007) performed for 208 toxin-producing clinical isolates of Clostridium difficile resulted in OPT-80 MICs ranging from 0.06 to 1 mu g/ml, with 90% of the isolates inhibited by a concentration of 0.5 mu g/ml. The in vitro activity of OPT-80 was independent of the susceptibilities of isolates to nine other antimicrobial agents.

引用

页码：4163 / 4165

页数：3

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