Environmental and Genetic Risk Factors in Obesity

被引：89

作者：

Hebebrand, Johannes ^{[1
]}

Hinney, Anke ^{[1
]}

机构：

[1] Univ Duisburg Essen, Rhein Kliniken Essen, Dept Child & Adolescent Psychiat, D-45147 Essen, Germany

来源：

CHILD AND ADOLESCENT PSYCHIATRIC CLINICS OF NORTH AMERICA | 2009年 / 18卷 / 01期

关键词：

Monogenic; Polygenic; Socioeconomic status; Television; BODY-MASS INDEX; GENOME-WIDE ASSOCIATION; CHILDHOOD OBESITY; PHYSICAL-ACTIVITY; SOCIOECONOMIC-STATUS; ENERGY-EXPENDITURE; SOCIAL-CLASS; FAT MASS; CHILDREN; WEIGHT;

D O I：

10.1016/j.chc.2008.07.006

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Because of its high prevalence and the associated medical and psychosocial risks, research into the causes of childhood obesity has experienced a tremendous upswing. Formal genetic data based on twin, adoption, and family studies lead to the conclusion that at least 50% of the interindividual variance of the body mass index (BMI; defined as weight in kilograms divided by height in meters squared) is due to genetic factors. As a result of the recent advent of genome-wide association studies, the first

引用

页码：83 / +

页数：14

共 89 条

[21] A war on obesity, not the obese [J].

Friedman, JM .

SCIENCE, 2003, 299 (5608) :856-858

[22]

Frohlich A., 1901, Wiener klinische Rundschau, V15, P833

[23]

Gahagan S., 2011, NELSON TXB PEDIAT

[24]

GARN SM, 1975, PEDIATRICS, V56, P306

[25] Melanocortin-4 receptor gene variant I103 is negatively associated with obesity [J].

Geller, F ;

Reichwald, K ;

Dempfle, A ;

Illig, T ;

Vollmert, C ;

Herpertz, S ;

Siffert, W ;

Platzer, M ;

Hess, C ;

Gudermann, T ;

Biebermann, H ;

Wichmann, HE ;

Schäfer, H ;

Hinney, A ;

Hebebrand, J .

AMERICAN JOURNAL OF HUMAN GENETICS, 2004, 74 (03) :572-581

[26] Television viewing as a cause of increasing obesity among children in the united states, 1986-1990 [J].

Gortmaker, SL ;

Must, A ;

Sobol, AM ;

Peterson, K ;

Colditz, GA ;

Dietz, WH .

ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 1996, 150 (04) :356-362

[27] Weight gain associated with increased food intake and low habitual activity levels in male adolescent schizophrenic inpatients treated with olanzapine [J].

Gothelf, D ;

Falk, B ;

Singer, P ;

Kairi, M ;

Phillip, M ;

Zigel, L ;

Poraz, I ;

Frishman, S ;

Constantini, N ;

Zalsman, G ;

Weizman, A ;

Apter, A .

AMERICAN JOURNAL OF PSYCHIATRY, 2002, 159 (06) :1055-1057

[28] Correlation between BMI, leisure habits and motor abilities in childhood (CHILT-Project) [J].

Graf, C ;

Koch, B ;

Kretschmann-Kandel, E ;

Falkowski, G ;

Christ, H ;

Coburger, S ;

Lehmacher, W ;

Bjarnason-Wehrens, B ;

Platen, P ;

Tokarski, W ;

Predel, HG ;

Dordel, S .

INTERNATIONAL JOURNAL OF OBESITY, 2004, 28 (01) :22-26

[29] Association between child and adolescent television viewing and adult health: a longitudinal birth cohort study [J].

Hancox, RJ ;

Milne, BJ ;

Poulton, R .

LANCET, 2004, 364 (9430) :257-262

[30] Binge-eating episodes are not characteristic of carriers of melanocortin-4 receptor gene mutations [J].

Hebebrand, J ;

Geller, F ;

Dempfle, A ;

Heinzel-Gutenbrunner, M ;

Raab, M ;

Gerber, G ;

Wermter, AK ;

Horro, FF ;

Blundell, J ;

Schäfer, H ;

Remschmidt, H ;

Herpertz, S ;

Hinney, A .

MOLECULAR PSYCHIATRY, 2004, 9 (08) :796-800

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