Lab-on-a-chip systems for biomedical and environmental monitoring

被引:110
作者
Gardeniers, JGE [1 ]
van den Berg, A [1 ]
机构
[1] Univ Twente, MESA Inst, BIOS Lab Chip Grp, NL-7500 AE Enschede, Netherlands
关键词
lab-on-a-chip; ion analysis; hydrodynamic chromatography; micromachining;
D O I
10.1007/s00216-003-2435-7
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
During the last decade, pocket-sized analytical equipment based on the "lab-on-a-chip" approach has become available. These chips, in combination with portable electronic equipment, are applicable in, for example, "point-of-care" ion analysis of body fluids, forensics, identification of explosives, tracking of pollution in environmental or waste waters, monitoring nutrients in agricultural or horticultural water, controlling quality in food production, or process control in chemical industry. This paper discusses several demonstrator systems with applications in these fields.
引用
收藏
页码:1700 / 1703
页数:4
相关论文
共 14 条
[1]   A pressure driven injection system for an ultra-flat chromatographic microchannel [J].
Chmela, E ;
Blom, MT ;
Gardeniers, JGE ;
van den Berg, A ;
Tijssen, R .
LAB ON A CHIP, 2002, 2 (04) :235-241
[2]   A chip system for size separation of macromolecules and particles by hydrodynamic chromatography [J].
Chmela, E ;
Tijssen, R ;
Blom, M ;
Gardeniers, HJGE ;
van den Berg, A .
ANALYTICAL CHEMISTRY, 2002, 74 (14) :3470-3475
[3]   Micromachining of buried micro channels in silicon [J].
de Boer, MJ ;
Tjerkstra, RW ;
Berenschot, JW ;
Jansen, HV ;
Burger, CJ ;
Gardeniers, JGE ;
Elwenspoek, M ;
van den Berg, A .
JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, 2000, 9 (01) :94-103
[4]   Silicon micromachined hollow microneedles for transdermal liquid transfer [J].
Gardeniers, JGE ;
Berenschot, JW ;
de Boer, MJ ;
Yeshurun, Y ;
Hefetz, M ;
van't Oever, R ;
van den Berg, A .
FIFTEENTH IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS, TECHNICAL DIGEST, 2002, :141-144
[5]   Quantitative analysis of anions at ppb/ppt levels with capillary electrophoresis and conductivity detection: Enhancement of system linearity and precision using an internal standard [J].
Haber, C ;
VanSaun, RJ ;
Jones, WR .
ANALYTICAL CHEMISTRY, 1998, 70 (11) :2261-2267
[6]  
Koroleff F., 1983, METHODS SEAWATER ANA, V2nd
[7]  
LUTTGE R, 2003, P MUTAS 2003 OCT 5 9, P511
[8]   Direct integration of micromachined pipettes in a flow channel for single DNA molecule study by optical tweezers [J].
Rusu, C ;
van't Oever, R ;
de Boer, MJ ;
Jansen, HV ;
Berenschot, JW ;
Bennink, ML ;
Kanger, JS ;
de Grooth, BG ;
Elwenspoek, M ;
Greve, J ;
Brugger, J ;
van den Berg, A .
JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, 2001, 10 (02) :238-246
[9]   2D-confined nanochannels fabricated by conventional micromachining [J].
Tas, NR ;
Berenschot, JW ;
Mela, P ;
Jansen, HV ;
Elwenspoek, M ;
van den Berg, A .
NANO LETTERS, 2002, 2 (09) :1031-1032
[10]   Nanofluidic bubble pump using surface tension directed gas injection [J].
Tas, NR ;
Berenschot, JW ;
Lammerink, TSJ ;
Elwenspoek, M ;
van den Berg, A .
ANALYTICAL CHEMISTRY, 2002, 74 (09) :2224-2227