Postpartum Treatment With Immunoglobulin Does Not Prevent Relapses of Multiple Sclerosis in the Mother

被引：12

作者：

Fragoso, Yara Dadalti ^{[1
]}

Adoni, Tarso ^{[2
]}

Alves-Leon, Soniza Vieira ^{[3
]}

Azambuja, Nerio Dutra, Jr. ^{[4
]}

Barreira, Amilton Antunes ^{[5
]}

Bidin Brooks, Joseph Bruno ^{[6
]}

Diniz Carneiro, Denise Sisteroli ^{[7
]}

Carvalho, Margarete J. ^{[8
]}

Claudino, Rinaldo ^{[9
]}

Comini-Frota, Elizabeth Regina ^{[10
]}

Domingues, Renan Barros ^{[11
]}

Finkelsztejn, Alessandro ^{[12
]}

Gama, Paulo Diniz ^{[13
]}

Brandao Giacomo, Maria Cristina ^{[14
]}

Gomes, Sidney ^{[15
,16
]}

Magno Goncalves, Marcus Vinicius ^{[17
]}

Grzesiuk, Anderson Kuntz ^{[18
]}

Kaimen-Maciel, Damacio Ramon ^{[19
]}

Mendes, Maria Fernanda ^{[20
]}

Oliveira Morales, Nivea Macedo ^{[21
]}

Morales, Rogerio Rizo ^{[21
]}

Muniz, Andre ^{[22
]}

Papais-Alvarenga, Regina Maria ^{[23
]}

Fiuza Parolin, Monica Koncke ^{[24
]}

Felix Ribeiro, Sonia Beatriz ^{[25
]}

Ruocco, Heloisa Helena ^{[26
]}

Salgado, Pedro Rippel ^{[27
]}

Siquineli, Fabio ^{[28
]}

Souza, Doralina Brum ^{[29
]}

Tosta, Elza Dias ^{[30
]}

Ferreira Vasconcelos, Claudia Cristina

Garcia Almeida, Sandra Maria ^{[31
,32
]}

Ribeiro Bernardes, Daniella Freire ^{[33
]}

Castro, Simone Nascimento ^{[34
]}

Diniz Gama, Rodrigo Assad ^{[35
]}

Resende Gomide, Fabrizio Antonio ^{[36
]}

Finkelzstejn, Juliana ^{[37
]}

Lopes, Josiane ^{[38
]}

de Barros Lourenco, Fabiani Honorato ^{[39
]}

Lourenco, Gisele A. ^{[40
]}

Silva Oliveira, Celso Luis ^{[41
]}

Meneses Oliveira, Francisco Tomaz ^{[42
,43
]}

Oliveira, Lucas Felix ^{[44
]}

Patroclo, Cristiane Borges ^{[40
]}

de Carvalho Jennings Pereira, Wildea Lice ^{[38
]}

Safanelli, Juliana ^{[17
]}

Sahdo, Alinne Martiniano ^{[30
]}

de Oliveira Saldanha, Patricia Correa ^{[11
]}

Shinzato, Yves Fumio ^{[13
]}

Barbosa Souza, Jorge Murilo ^{[9
]}

机构：

[1] Univ Metropolitana Santos, Sch Med, Dept Neurol, Santos, Brazil

[2] Hosp Sirio Libanes, Dept Neurol, Sao Paulo, Brazil

[3] Univ Fed Rio de Janeiro, Dept Neurol, Rio De Janeiro, Brazil

[4] Neurol & Neurosurg Passo Fundo, Passo Fundo, Brazil

[5] Univ Sao Paulo, Dept Neurol, BR-14049 Ribeirao Preto, Brazil

[6] Univ Metropolitana Santos, Dept Neurol, Santos, Brazil

[7] Univ Fed Goias, Dept Neurol, Goiania, Go, Brazil

[8] Fundacao ABC, Dept Neurol, Santo Andre, Brazil

[9] Univ Fed Santa Catarina, Dept Neurol, Florianopolis, SC, Brazil

[10] Univ Fed Minas Gerais, Dept Neurol, Belo Horizonte, MG, Brazil

[11] Santa Casa Vitoria, Dept Neurol, Sch Hlth Sci, Vitoria, Brazil

[12] Hosp Clin Porto Alegre, Dept Neurol, Porto Alegre, RS, Brazil

[13] Pontificia Univ Catolica, Dept Neurol, Sorocaba, Brazil

[14] Neurol Clin, Sao Paulo, Brazil

[15] Hosp Beneficencia Portuguesa, Dept Neurol, Sao Paulo, Brazil

[16] Hosp Paulistano, Sao Paulo, Brazil

[17] Univ Regiao Joinville, Dept Neurol, Joinville, Brazil

[18] Rehabil Ctr Dom Aquino Correa, Dept Neurol, Cuiaba, Brazil

[19] Univ Estadual Londrina, Dept Neurol, Londrina, Brazil

[20] Santa Casa Sao Paulo, Dept Neurol, Sao Paulo, Brazil

[21] Univ Fed Uberlandia, Dept Neurol, BR-38400 Uberlandia, MG, Brazil

[22] Hosp Sao Rafael, Dept Neurol, Salvador, BA, Brazil

[23] Univ Fed Estado Rio de Janeiro, Dept Neurol, Rio De Janeiro, Brazil

[24] Neurol Clin, Curitiba, Parana, Brazil

[25] Univ Fed Triangulo Mineiro, Dept Neurol, Uberaba, Brazil

[26] MS Ctr Jundiai, Dept Neurol, Jundiai, Brazil

[27] Univ Fed Mato Grosso do Sul, Dept Neurol, Campo Grande, Brazil

[28] Univ Reg Blumenau, Dept Neurol, Blumenau, Brazil

[29] Univ Sao Paulo, Dept Neurol, BR-14049 Ribeirao Preto, Brazil

[30] Hosp Base Distrito Fed, Dept Neurol, Brasilia, DF, Brazil

[31] Univ Fed Estado Rio de Janeiro, Dept Neurol, Rio De Janeiro, Brazil

[32] Univ Fed Rio de Janeiro, Dept Neurol, Rio De Janeiro, Brazil

[33] Hosp Sao Rafael, Dept Neurol, Salvador, BA, Brazil

[34] Univ Fed Mato Grosso do Sul, Dept Neurol, Campo Grande, Brazil

[35] Pontificia Univ Catolica, Dept Neurol, Sorocaba, Brazil

[36] Univ Fed Triangulo Mineiro, Dept Neurol, Uberaba, Brazil

[37] Hosp Clin Porto Alegre, Dept Neurol, Porto Alegre, RS, Brazil

[38] Univ Estadual Londrina, Dept Neurol, Londrina, Brazil

[39] Univ Fed Mato Grosso do Sul, Dept Neurol, Campo Grande, Brazil

[40] Univ Fed Rio de Janeiro, Dept Neurol, Rio De Janeiro, Brazil

[41] Univ Metropolitana Santos, Dept Neurol, Santos, Brazil

[42] Hosp Beneficencia Portuguesa, Dept Neurol, Sao Paulo, Brazil

[43] Hosp Paulistano, Sao Paulo, Brazil

[44] Univ Fed Triangulo Mineiro, Dept Neurol, Uberaba, Brazil

来源：

HEALTH CARE FOR WOMEN INTERNATIONAL | 2015年 / 36卷 / 10期

关键词：

DISEASE-MODIFYING DRUGS; INTRAVENOUS IMMUNOGLOBULIN; PREGNANCY; WOMEN;

D O I：

10.1080/07399332.2014.948627

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Multiple sclerosis (MS) is a chronic, neurological, immune-mediated disease that can worsen in the postpartum period. There is no consensus on the use of immunoglobulin for prevention of disease relapses after delivery. We have shown that the controversial beneficial effect of immunoglobulin given immediately after birth could not be observed in patients with MS.

引用

页码：1072 / 1080

页数：9

共 18 条

[1] Effect of intravenous immunoglobulin treatment on pregnancy and postpartum-related relapses in multiple sclerosis [J].

Achiron, A ;

Kishner, I ;

Dolev, M ;

Stern, Y ;

Dulitzky, M ;

Schiff, E ;

Achiron, R .

JOURNAL OF NEUROLOGY, 2004, 251 (09) :1133-1137

[2] Rate of pregnancy-related relapse in multiple sclerosis [J].

Confavreux, C ;

Hutchinson, M ;

Hours, MM ;

Cortinovis-Tourniaire, P ;

Moreau, T .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (05) :285-291

[3] Exclusive Breastfeeding in Southern Brazil: Prevalence and Associated Factors [J].

do Nascimento, Maria Beatriz R. ;

Moura Reis, Marco A. ;

Franco, Selma Cristina ;

Issler, Hugo ;

Ferraro, Alexandre A. ;

Grisi, Sandra Josefina F. E. .

BREASTFEEDING MEDICINE, 2010, 5 (02) :79-85

[4] Intravenous immunoglobulins as therapeutic option in the treatment of multiple sclerosis [J].

Dudesek, Ales ;

Zettl, Uwe K. .

JOURNAL OF NEUROLOGY, 2006, 253 (Suppl 5) :50-58

[5] Can we face the challenge of expanding use of intravenous immunoglobulin in neurology? [J].

Elovaara, I. ;

Hietaharju, A. .

ACTA NEUROLOGICA SCANDINAVICA, 2010, 122 (05) :309-315

[6] Intravenous immunoglobulin in relapsing-remitting multiple sclerosis - A dose-finding trial [J].

Fazekas, F. ;

Lublin, F. D. ;

Li, D. ;

Freedman, M. S. ;

Hartung, H. P. ;

Rieckmann, P. ;

Sorensen, P. Soelberg ;

Maas-Enriquez, M. ;

Sommerauer, B. ;

Hanna, K. .

NEUROLOGY, 2008, 71 (04) :265-271

[7] The Brazilian database on pregnancy in multiple sclerosis [J].

Finkelsztejn, A. ;

Fragoso, Y. D. ;

Ferreira, M. L. B. ;

Lana-Peixoto, M. A. ;

Alves-Leon, S. V. ;

Gomes, S. ;

Damasceno, B. P. ;

Mendes, M. F. ;

Salgado, P. R. ;

Correa, E. C. ;

Comini-Frota, E. R. ;

Diniz, D. S. ;

Gama, P. D. ;

Kaimen-Maciel, D. R. ;

Morales, R. R. ;

Arruda, W. O. ;

Grzesiuk, A. K. ;

Khouri, J. M. N. ;

Lopes, J. S. ;

Rocha, C. F. ;

Domingues, R. ;

Goncalves, M. V. M. ;

Lorenti, M. A. ;

Parolin, M. K. F. ;

Siquineli, F. ;

Tosta, E. D. ;

Brooks, J. B. B. ;

Gallina, A. S. ;

Melges, L. D. M. ;

Ruocco, H. H. .

CLINICAL NEUROLOGY AND NEUROSURGERY, 2011, 113 (04) :277-280

[8] Long-Term Use of Glatiramer Acetate by 11 Pregnant Women with Multiple Sclerosis A Retrospective, Multicentre Case Series [J].

Fragoso, Yara D. ;

Finkelsztejn, Alessandro ;

Kaimen-Maciel, Damacio R. ;

Grzesiuk, Anderson K. ;

Gallina, Andre S. ;

Lopes, Josiane ;

Morales, Nivea M. O. ;

Alves-Leon, Soniza V. ;

de Almeida, Sandra M. G. .

CNS DRUGS, 2010, 24 (11) :969-976

[9] The effects of long-term exposure to disease-modifying drugs during pregnancy in multiple sclerosis [J].

Fragoso, Yara Dadalti ;

Boggild, Mike ;

Angel Macias-Islas, Miguel ;

Carrad, Adriana ;

Schaerer, Kirsty Deborah ;

Aguayo, Adriana ;

Garcia de Almeida, Sandra Maria ;

Alvarenga, Marcos Papais ;

Papais Alvarenga, Regina Maria ;

Alves-Leon, Soniza Vieira ;

Arruda, Walter Oleschko ;

Bidin Brooks, Joseph Bruno ;

Regina Comini-Frota, Elizabeth ;

Brito Ferreira, Maria Lucia ;

Finkelsztejn, Alessandro ;

Szymanski Finkelsztejn, Juliana Marcon ;

de Freitas, Lucas Dias ;

Gallina, Andre Serafin ;

da Gama, Paulo Diniz ;

Georgetto, Sergio ;

Giacomo, Maria Cristina B. ;

Gomes, Sidney ;

Magno Goncalves, Marcus Vinicius ;

Grzesiuk, Anderson Kuntz ;

Kaimen-Maciel, Damacio Ramon ;

Lopes, Josiane ;

Lourenco, Giselle A. ;

Malfetano, Fabiola Rachid ;

Oliveira Morales, Nivea Macedo ;

Morales, Rogerio de Rizo ;

Silva Oliveira, Celso Luis ;

Onaha, Patricia ;

Patroclo, Cristiane ;

Felix Ribeiro, Sonia Beatriz ;

Gonsalves Jube Ribeiro, Taysa Alexandrino ;

Salminen, Heidi Johanna ;

Santoro, Patricia ;

Seefeld, Marcos ;

Soares, Paula Vallegas ;

Tarulla, Adriana ;

Ferreira Vasconcelos, Claudia Cristina .

CLINICAL NEUROLOGY AND NEUROSURGERY, 2013, 115 (02) :154-159

[10] PREGNANCY AND MULTIPLE SCLEROSIS The initial results from a Brazilian database [J].

Fragoso, Yara Dadalti ;

Finkelsztejn, Alessandro ;

Comini-Frota, Elizabeth Regina ;

da Gama, Paulo Diniz ;

Grzesiuk, Ansderson Kuntz ;

Netto Khouri, Jussara Mathias ;

Alves-Leon, Soniza Vieira ;

Morales, Rogerio de Rizo ;

Lana-Peixoto, Marco Aurelio ;

da Rocha, Cristiane Franklin .

ARQUIVOS DE NEURO-PSIQUIATRIA, 2009, 67 (3A) :657-660

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