学术探索
学术期刊
新闻热点
数据分析
智能评审

WNT signaling and lymphocyte development

被引：108
作者：
van de Wetering, M [1 ]
de Lau, W [1 ]
Clevers, H [1 ]
机构：
[1] UMC Utrecht, Dept Immunol, NL-3584 CX Utrecht, Netherlands
来源：
CELL | 2002年 / 109卷
关键词：
D O I：
10.1016/S0092-8674(02)00709-2
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Developmental studies in model organisms have revealed that cell fate decisions are governed by only a handful of highly conserved signal transduction cascades. Recent data indicate that at least two of these, the Wnt and the Notch cascades, have been recruited by the vertebrate immune system to control early lymphopoiesis.
引用
收藏
页码：S13 / S19
页数：7
相关论文
共 66 条
  • [1] beta-catenin is a target for the ubiquitin-proteasome pathway
    Aberle, H
    Bauer, A
    Stappert, J
    Kispert, A
    Kemler, R
    [J]. EMBO JOURNAL, 1997, 16 (13) : 3797 - 3804
  • [2] Barker N, 2000, ADV CANCER RES, V77, P1
  • [3] Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β
    Behrens, J
    Jerchow, BA
    Würtele, M
    Grimm, J
    Asbrand, C
    Wirtz, R
    Kühl, M
    Wedlich, D
    Birchmeier, W
    [J]. SCIENCE, 1998, 280 (5363) : 596 - 599
  • [4] Functional interaction of beta-catenin with the transcription factor LEF-1
    Behrens, J
    vonKries, JP
    Kuhl, M
    Bruhn, L
    Wedlich, D
    Grosschedl, R
    Birchmeier, W
    [J]. NATURE, 1996, 382 (6592) : 638 - 642
  • [5] A new member of the frizzled family from Drosophila functions as a Wingless receptor
    Bhanot, P
    Brink, M
    Samos, CH
    Hsieh, JC
    Wang, YS
    Macke, JP
    Andrew, D
    Nathans, J
    Nusse, R
    [J]. NATURE, 1996, 382 (6588) : 225 - 230
  • [6] Linking colorectal cancer to Wnt signaling
    Bienz, M
    Clevers, H
    [J]. CELL, 2000, 103 (02) : 311 - 320
  • [7] Brannon M, 1999, DEVELOPMENT, V126, P3159
  • [8] ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCR alpha enhancer function
    Bruhn, L
    Munnerlyn, A
    Grosschedl, R
    [J]. GENES & DEVELOPMENT, 1997, 11 (05) : 640 - 653
  • [9] THE HLEF/TCF-1-ALPHA HMG PROTEIN CONTAINS A CONTEXT-DEPENDENT TRANSCRIPTIONAL ACTIVATION DOMAIN THAT INDUCES THE TCR-ALPHA ENHANCER IN T-CELLS
    CARLSSON, P
    WATERMAN, ML
    JONES, KA
    [J]. GENES & DEVELOPMENT, 1993, 7 (12A) : 2418 - 2430
  • [10] Drosophila Tcf and Groucho interact to repress Wingless signalling activity
    Cavallo, RA
    Cox, RT
    Moline, MM
    Roose, J
    Polevoy, GA
    Clevers, H
    Peifer, M
    Bejsovec, A
    [J]. NATURE, 1998, 395 (6702) : 604 - 608
1234567