Linking colorectal cancer to Wnt signaling

被引:1373
作者
Bienz, M
Clevers, H
机构
[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England
[2] Univ Med Ctr, Dept Immunol, NL-3508 GA Utrecht, Netherlands
[3] Univ Med Ctr, Ctr Biomed Genet, NL-3508 GA Utrecht, Netherlands
关键词
D O I
10.1016/S0092-8674(00)00122-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:311 / 320
页数:10
相关论文
共 109 条
  • [1] beta-catenin is a target for the ubiquitin-proteasome pathway
    Aberle, H
    Bauer, A
    Stappert, J
    Kispert, A
    Kemler, R
    [J]. EMBO JOURNAL, 1997, 16 (13) : 3797 - 3804
  • [2] Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development
    Ahmed, Y
    Hayashi, S
    Levine, A
    Wieschaus, E
    [J]. CELL, 1998, 93 (07) : 1171 - 1182
  • [3] Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways
    Axelrod, JD
    Miller, JR
    Shulman, JM
    Moon, RT
    Perrimon, N
    [J]. GENES & DEVELOPMENT, 1998, 12 (16) : 2610 - 2622
  • [4] NH2-terminal deletion of beta-catenin results in stable colocalization of mutant beta-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion
    Barth, AIM
    Pollack, AL
    Altschuler, Y
    Mostov, KE
    Nelson, WJ
    [J]. JOURNAL OF CELL BIOLOGY, 1997, 136 (03) : 693 - 706
  • [5] Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β
    Behrens, J
    Jerchow, BA
    Würtele, M
    Grimm, J
    Asbrand, C
    Wirtz, R
    Kühl, M
    Wedlich, D
    Birchmeier, W
    [J]. SCIENCE, 1998, 280 (5363) : 596 - 599
  • [6] Functional interaction of beta-catenin with the transcription factor LEF-1
    Behrens, J
    vonKries, JP
    Kuhl, M
    Bruhn, L
    Wedlich, D
    Grosschedl, R
    Birchmeier, W
    [J]. NATURE, 1996, 382 (6592) : 638 - 642
  • [7] Differential molecular interactions of β-catenin and plakoglobin in adhesion, signaling and cancer
    Ben-Ze'ev, A
    Geiger, B
    [J]. CURRENT OPINION IN CELL BIOLOGY, 1998, 10 (05) : 629 - 639
  • [8] A new member of the frizzled family from Drosophila functions as a Wingless receptor
    Bhanot, P
    Brink, M
    Samos, CH
    Hsieh, JC
    Wang, YS
    Macke, JP
    Andrew, D
    Nathans, J
    Nusse, R
    [J]. NATURE, 1996, 382 (6588) : 225 - 230
  • [9] APC: the plot thickens
    Bienz, M
    [J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 1999, 9 (05) : 595 - 603
  • [10] CADHERIN EXPRESSION IN CARCINOMAS - ROLE IN THE FORMATION OF CELL-JUNCTIONS AND THE PREVENTION OF INVASIVENESS
    BIRCHMEIER, W
    BEHRENS, J
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 1994, 1198 (01): : 11 - 26